Erivedge contains the active ingredient vismodegib, which is a hedgehog pathway inhibitor, in its crystalline free base form. It is available as a capsule for oral administration, with each capsule containing 150 mg of vismodegib. Key inactive ingredients in the capsule include microcrystalline cellulose, lactose monohydrate, and magnesium stearate.
How should I use this medication?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. You can take it with or without food. If it upsets your stomach, take it with food. Do not take it more often than directed. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication.
Talk to your care team if you or your partner wish to become pregnant or think either of you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or for 24 months after the last dose. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 24 months after the last dose. Talk to your care team about reliable forms of contraception. Do not father a child while taking this medication and for 3 months after the last dose. Use a condom during sex while taking this medication and for 3 months after the last dose.
Do not breast-feed while taking this medication and for 24 months after the last dose.
Do not donate sperm while taking this medication or for 3 months after the last dose.
Do not donate blood while you are talking this medication or for 24 months after the last dose. Donated blood may contain enough of this medication to cause birth defects in a fetus if transfused to someone who is pregnant.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
What are the most serious risks of this medication?
Males who get this medicine must use a condom during sex with female partners who can get pregnant. If you get a woman pregnant during treatment, the baby could have severe birth defects or die before they are born. You may need to continue to avoid getting a female pregnant after stopping the medicine. The length of time depends on the medication. Talk to your healthcare provider about how long you should continue to wear condoms after stopping the medicine. Tell your healthcare provider right away if your partner becomes pregnant while you are taking this medicine.
This medication may cause serious birth defects if taken during pregnancy. Do not take this medication if you are pregnant.
Source: This information is sourced from Elsevier Inc.
The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.
Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.
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