What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Heart disease
- Eye disease
- High or low levels of electrolytes, such as magnesium, potassium, or sodium in your blood
- History of blood diseases, such as aplastic anemia
- Irregular heartbeat or rhythm
- Lung disease
- An unusual or allergic reaction to osimertinib, other medications, foods, dyes, or preservatives
- Pregnant or trying to get pregnant
- Breast-feeding
What may interact with this medication?
Do not take this medication with any of the following:
- Cisapride
- Dronedarone
- Ketoconazole
- Levoketoconazole
- Pimozide
- Thioridazine
This medication may interact with the following:
- Fexofenadine
- Other medications that cause heart rhythm changes
- Rifampin
- Rosuvastatin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
Males who get this medication must use a condom during sex with females who can get pregnant. If you get a woman pregnant, there is potential for serious harm to an unborn child. You will need to continue wearing a condom for 4 months after stopping the medication. Tell your care team right away if you think your partner might be pregnant.
Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 6 weeks after stopping it. Do not breast-feed while taking this medication and for 2 weeks after stopping it.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.
Tell your care team right away if you have any change in your eyesight.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.
Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your care team you are receiving this medication.