What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Albinism
- Eye problems, such as cataracts or loss of the lens of the eyes
- Heart disease
- Liver disease
- Lupus
- Porphyria
- History of arsenic therapy
- History of x-ray therapy
- Skin cancer
- Skin photosensitivity problems
- Xeroderma pigmentosum
- An unusual or allergic reaction to methoxsalen, other medications, foods, dyes, or preservatives
- Pregnant or trying to get pregnant
- Breast-feeding
What may interact with this medication?
- Anthralin
- Coal tar
- Diuretics, such as hydrochlorothiazide
- Griseofulvin
- Medical dyes, such as methylene blue, toluidine blue, rose bengal, methyl orange
- Medications for seizures, such as ethotoin, fosphenytoin, phenytoin
- Nalidixic acid
- Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine
- Retinoids, such as bexarotene, tazarotene, tretinoin
- Some antibiotics, such as ciprofloxacin, sulfamethoxazole, tetracycline
- Some bacteriostatic soaps
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication. Tell your care team if your symptoms do not start to get better or if they get worse.
This medication may cause cataracts or other vision changes. You should have regular eye exams while taking this medication. Tell your care team right away if you have changes in your eyesight.
Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer, including skin cancer, if you take this medication.
This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Stay out of the sun for 24 hours before a UV treatment and at least 8 hours after taking this medication, or as directed by your care team.
For 24 hours after you take this medication, wear wrap-around sunglasses that block all UV light whenever you can see any sunlight.
Do not switch between hard- and soft-gelatin capsules of this medication. This may change the timing of your UV treatment.
What are the most serious risks of this medication?
This medicine should only be given by a healthcare provider who has special training and experience in using it. The treatment has severe side effects. These include eye damage, aging of the skin, and skin cancer.