Adynovate ratings & reviews

Antihemophilic Factor (Recombinant), PEGylated
Company: TPNA
Brand: Adynovate
+1 more
Adynovate, Jivi
Drug class: Blood and Blood Forming Organs
+3 more
Blood and Blood Forming Organs, Antihemorrhagics, Hemostatics, Blood Coagulation Factors
Overall rating
3.5
full star full star full star half star empty star
Ranked #4
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.6/5
Safety
3.7/5
Tolerability
3.5/5
Accessibility
3.3/5
Adherence
3.5/5

Sermo AI Overview

  • Adynovate exhibits mixed reviews regarding its efficacy and safety among healthcare professionals, with overall effectiveness ratings ranging around 3.0 to 5.0. While many users find it manageable to use, concerns about its pegylation process and a preference for alternative treatments persist.
  • The overall safety ratings for Adynovate are moderately better at approximately 4.0; however, user satisfaction remains lukewarm with an average score of 2.6, indicating that while it is generally tolerated, many users have reservations about its efficacy.
  • Accessibility to Adynovate seems relatively better among users, but mixed sentiments about its effectiveness and concerns regarding the treatment's pegylation process highlight the need for more clarity in its use for bleeding prophylaxis.
  • While users generally report reasonable tolerability with Adynovate, healthcare providers express mixed feelings about its overall efficacy and adherence, prompting a need for ongoing evaluation and consideration of alternative therapies.
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Based on insights from Sermo’s triple verified physicians

Description

Adynovate is a brand name drug containing Antihemophilic Factor (Recombinant), PEGylated, which is a form of recombinant human coagulation factor VIII. It is formulated as a lyophilized powder for reconstitution and is intended for intravenous injection, available in various dosage strengths from 250 to 3000 IU. The drug contains polyethylene glycol as part of its active ingredient modification and is produced without preservatives or additives of human or animal origins. It is designed to increase blood clotting factors in individuals with hemophilia A to manage their bleeding episodes.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected into a vein. It is usually given by your care team in a hospital or clinic setting.

If you get this medication at home, you will be taught how to prepare and give it. Use exactly as directed. Take it as directed on the prescription label at the same time every day. Keep taking it unless your care team tells you to stop.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

Talk to your care team about the use of this medication in children. While it may be prescribed for children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you get this medication at the hospital or clinic: It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

If you give yourself this medication at home: If you miss a dose, take it as soon as you can, then continue your normal schedule. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team with questions.

Where should I keep my medication?

Keep out of the reach of children and pets.

This medication is usually given in a hospital or clinic. If you are using this medication at home, you will be instructed on how to store this medication. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Infection—fever, chills, cough, or sore throat

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • General discomfort and fatigue
  • Headache
  • Joint pain
  • Muscle pain
  • Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • An unusual or allergic reaction to antihemophilic factor, cow, hamster, or mouse proteins, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may need blood work while taking this medication.

Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.

Some products are derived from human plasma, and there is a small risk that these products may contain certain types of virus or bacteria. All products are processed to kill most viruses and bacteria. If you have questions concerning the risk of viral infections, discuss them with your doctor or care team.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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