ARAZLO is a white to off-white lotion containing 0.045% tazarotene, which belongs to the acetylenic class of retinoids. It is intended for topical administration. The lotion includes inactive ingredients such as carbomer copolymer type B, carbomer homopolymer type A, diethyl sebacate, edetate disodium dihydrate, and light mineral oil.

How should I use this medication?

This medication is for external use only. Do not take by mouth. Follow the directions on the prescription label. Make sure the skin is clean and dry. If you use other medications on your skin, apply this medication at a different time of the day. Apply just enough lotion to cover the affected areas. Rub in gently. Wash your hands after applying this medication. Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 9 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat -Burning, itching, crusting, or peeling of treated skin Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): -Mild skin irritation, redness, or dryness -Sensitivity to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions: -Sensitivity to the sun or sunburn -Skin cancer or family history of skin cancer -Skin conditions or sensitivity -An unusual or allergic reaction to tazarotene, vitamin A, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding

What may interact with this medication?

-Medications that may dry your skin, such as benzoyl peroxide or salicylic acid -Medications that may increase your sensitivity to the sun, such as tetracycline, thiazide diuretics, quinolone antibiotics (ciprofloxacin, levofloxacin, and others), phenothiazines (chlorpromazine, fluphenazine, perphenazine, thioridazine, trifluoperazine), and sulfa medications -Vitamin A supplements

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects. Do not get this medication in your eyes. If you do, rinse out with plenty of cool tap water. Use this medication with caution if you are also using other products with a strong skin drying effect. This may include products with a high alcohol content, astringents, spices, the peel of lime or other citrus, medicated soaps or shampoos, permanent wave solutions, electrolysis, hair removers or waxes, or any other preparations or processes that might dry or irritate your skin. Talk to care team before using these products. This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths. Avoid weather extremes because they may be more irritating to patients using this medication.