Ziana ratings & reviews

Clindamycin, Tretinoin
Company: Bausch
Brand: Ziana
Drug class: Dermatologicals
+3 more
Dermatologicals, Acne Agents, Topical Agents for Acne, Topical Anti-Infective and Retinoid Combinations for Acne
Overall rating
3.4
full star full star full star empty star empty star
Ranked #44
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.7/5
Safety
3.6/5
Tolerability
3.4/5
Accessibility
3.0/5
Adherence
3.5/5

Sermo AI Overview

  • Ziana is generally well tolerated and can effectively treat mild to moderate acne, but its high cost and limited spray volume often create accessibility challenges for patients, particularly when insurance coverage is lacking.
  • Physician feedback emphasizes Ziana's effectiveness for acne treatment; however, concerns about its cost and accessibility remain prevalent, making it difficult for some patients to obtain the medication due to insurance issues.
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Based on insights from Sermo’s triple verified physicians

Description

Ziana is a gel that contains two active ingredients: clindamycin phosphate, a water-soluble ester form of an antibiotic, and tretinoin, a member of the retinoid family. The gel is formulated with 1.2% clindamycin phosphate and 0.025% tretinoin, and includes inactive ingredients like anhydrous citric acid, butylated hydroxytoluene, and others. It is commonly used to treat acne by combining the antibiotic properties of clindamycin with the skin renewal effects of tretinoin.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is for external use only. Do not take by mouth. Wash your hands before and after use. Do not get it in your eyes. If you do, rinse your eyes with plenty of cool tap water. Use it as directed on the prescription label at the same time every day. Do not use it more often than directed. Use the medication for the full course as directed by your care team, even if you think you are better. Do not stop using it unless your care team tells you to stop it early.

Apply a thin film of the medication to the affected area.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Protect from light and moisture. Keep the container tightly closed. Avoid exposure to extreme heat.

Get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Burning, itching, crusting, or peeling of treated skin
  • Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Mild skin irritation, redness, or dryness
  • Sensitivity to light

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
  • Large area of burned or damaged skin
  • Skin conditions or sensitivity
  • Stomach or intestine problems like colitis
  • An unusual or allergic reaction to clindamycin, tretinoin, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

  • Erythromycin
  • Muscle relaxers used during surgery
  • Other skin products that contain alcohol, astringents, spices or lime

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. It may be some time before you see the benefit from this medication. Tell your care team if your symptoms do not start to get better or if they get worse. Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery. This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps or tanning beds/booths. Do not use other products that dry the skin. Examples include abrasive cleaners or products with alcohol in them. Do not use other acne products on the same areas of the skin as this one unless your care team tells you to use both.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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