AZEDRA ratings & reviews

Iobenguane I-131
Company: Progenics
Brand: AZEDRA
Drug class: Antineoplastic and Immunomodulating Agents
+3 more
Antineoplastic and Immunomodulating Agents, Antineoplastics, Therapeutic Antineoplastic Radiopharmaceuticals, Other Therapeutic Radiopharmaceuticals
Overall rating
3.5
full star full star full star half star empty star
Ranked #1
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.5/5
Safety
3.6/5
Tolerability
3.4/5
Accessibility
3.2/5
Adherence
3.6/5

Sermo AI Overview

  • Azedra has low efficacy ratings, particularly around 2.0, from both urologists and hematology oncology specialists, suggesting it may not be very effective for treating pheochromocytoma.
  • Many healthcare specialists believe that surgical treatment is often sufficient for pheochromocytoma, making Azedra an unnecessary option in most cases, which further emphasizes its limited role in treatment.
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Based on insights from Sermo’s triple verified physicians

Description

AZEDRA is a drug where the active ingredient is Iobenguane I 131. It is designed to release radiation energy to slow or stop the spread of cancer cells or other irregular cells.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is infused into a vein. It is given by a care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. While it may be given to children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Dry cough, shortness of breath or trouble breathing
  • Increase in blood pressure
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Dizziness
  • Fatigue
  • Nausea
  • Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • High blood pressure
  • Kidney disease
  • Thyroid disease
  • An unusual or allergic reaction to iobenguane I-131, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

  • Certain medications for blood pressure, such as labetalol or reserpine
  • Certain medications for depression, such as amitriptyline
  • Decongestants, such as pseudoephedrine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may need blood work done while you are taking this medication.

Talk to your care team about how to prepare for your treatment. Drink at least 2 Liters of fluid a day before and for 1 week after your treatment dose. This will help reduce radiation exposure to your bladder.

Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancers if you take this medication.

Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 7 months after your last dose. Contraception is recommended while taking this medication and for 7 months after the last dose. Your care team can help you find the option that works for you.

If your partner can get pregnant, use a condom during sex while taking this medication and for 4 months after the last dose.

Do not breastfeed while taking this medication and for at least 80 days after your last dose.

This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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