Xofigo ratings & reviews

Radium Ra 223 dichloride
Company: Bayer
Brand: Xofigo
Drug class: Antineoplastic and Immunomodulating Agents
+3 more
Antineoplastic and Immunomodulating Agents, Antineoplastics, Therapeutic Antineoplastic Radiopharmaceuticals, Other Therapeutic Radiopharmaceuticals
Overall rating
3.6
full star full star full star half star empty star
Ranked #15
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.7/5
Safety
3.6/5
Tolerability
3.6/5
Accessibility
3.2/5
Adherence
3.6/5

Sermo AI Overview

  • Xofigo has shown positive effects on the quality of life for patients with hormone refractory prostate cancer and bone metastases, improving mobility and daily activities for many individuals.
  • While Xofigo is effective for many patients, challenges related to access and insurance coverage can complicate its initial administration, indicating a need for improved support systems.
  • Oncologists generally rate Xofigo positively for efficacy and safety; however, some healthcare providers highlight accessibility issues, necessitating attention to distribution and patient access.
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Based on insights from Sermo’s triple verified physicians

Description

The brand name of the drug is Xofigo, which contains the active ingredient radium-223 dichloride, an alpha particle-emitting pharmaceutical. Xofigo is a radiotherapeutic drug supplied as a sterile solution for intravenous administration, with each vial containing 6 mL of the solution. Key inactive ingredients include sodium chloride, sodium citrate, and hydrochloric acid for pH adjustment. It is designed to emit radiation primarily in the form of alpha particles to potentially slow or stop the spread of prostate cancer cells.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected into a vein. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Diarrhea
  • Nausea
  • Swelling of the ankles, hands, or feet
  • Vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Blood disorders
  • Low blood cell levels (white cells, red cells, and platelets)
  • Pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

Interactions have not been studied.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for checks on your progress. This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.

You may need blood work done while you are taking this medication.

Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer if you take this medication.

This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.

Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medication.

If your partner can get pregnant, use a condom during sex while taking this medication and for 6 months after the last dose. Tell your care team right away if you think your partner might be pregnant. This medication can cause serious birth defects.

This medication may cause infertility. Talk to your care team if you are concerned about your fertility.

Do not donate sperm while taking this medication and for 6 months after the last dose.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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