What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Eye disease
- High levels of phosphorous in the blood
- Kidney disease
- Liver disease
- Vision problems
- An unusual or allergic reaction to erdafitinib, other medications, foods, dyes, or preservatives
- If you or your partner are pregnant or trying to get pregnant
- Breastfeeding
What may interact with this medication?
Do not take this medication with any of the following:
This medication may also interact with the following:
- Certain antibiotics, such as erythromycin, clarithromycin
- Certain antifungals, such as ketoconazole, itraconazole, posaconazole
- Certain antivirals for HIV or hepatitis
- Certain medications for seizures, such as carbamazepine, phenobarbital, phenytoin
- Certain medications that can change blood phosphorous levels
- Grapefruit or grapefruit juice
- St. John's wort
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored carefully while you are receiving this medication.
This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
This medication may cause dry eyes and blurred vision. If you wear contact lenses, you may feel some discomfort. Lubricating eye drops may help. See your care team if the problem does not go away or is severe.
Your vision may be tested before and during use of this medication.
Tell your care team right away if you have any change in your eyesight.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.
Your blood phosphorous levels will be monitored. Do not take more than 600 to 800 mg per day of phosphate. Tell your care team if you have painful skin lesions, any muscle cramps, or numbness and tingling around your mouth.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 1 month after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 1 month after the last dose. Your care team can help you find the option that works for you.
If your partner can get pregnant, use a condom during sex while taking this medication and for 1 month after the last dose.
Do not breastfeed while taking this medication and for 1 month after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.