Korlym is the brand name for mifepristone, which is a cortisol receptor blocker. It comes as an oral tablet containing 300 mg of mifepristone. Some of the key inactive ingredients include silicified microcrystalline cellulose, sodium starch glycolate, and magnesium stearate.
How should I use this medication?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. Take it with food. Do not take this medication with grapefruit juice. Keep taking it unless your care team tells you to stop.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. You will need blood work done while you are taking this medication.
This medication may affect blood sugar levels. If you have diabetes, check with your care team before you change your diet or the dose of your diabetic medication.
Keep the MedGuide for this medication. If you need emergency medical care, show your care team the MedGuide. Tell the care team that you have taken this medication.
Talk to your care team if you or your partner wish to become pregnant or think either of you might be pregnant. This medication can cause serious birth defects if taken during pregnancy or for 1 month after stopping treatment. A negative pregnancy test is required before starting this medication. A reliable form of contraception is recommended while taking this medication and for 1 month after stopping treatment. Talk to your care team about effective forms of contraception.
Estrogen and progestin hormones may not work as well while you are taking medication. A barrier contraceptive, such as a condom or diaphragm, is recommended if you are using these hormones for contraception while taking this medication and for 1 month after stopping this medication. Talk to your care team about effective forms of contraception.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.
What are the most serious risks of this medication?
Do not take Korlym to treat Cushing's disease if you are pregnant. It can cause harm to an unborn baby.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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