Bydureon BCise ratings & reviews

Exenatide
Company: AZN
Brand: Bydureon BCise
+1 more
Bydureon BCise, Byetta
Drug class: Alimentary Tract and Metabolism
+4 more
Alimentary Tract and Metabolism, Antidiabetic Agents, Blood Glucose Lowering Agents, excluding Insulins, Incretin mimetics Antidiabetics, Glucagon-like Peptide-1 (GLP-1) Receptor Agonists
Overall rating
3.4
full star full star full star empty star empty star
Ranked #44
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.6/5
Safety
3.6/5
Tolerability
3.4/5
Accessibility
3.2/5
Adherence
3.3/5

Sermo AI Overview

  • Bydureon BCise is considered generally effective for managing type 2 diabetes, with many healthcare professionals commenting positively on its efficacy. However, challenges around patient adherence and tolerability may affect its use.
  • While Bydureon BCise has favorable overall safety ratings, some concerns exist regarding gastrointestinal issues and injection site reactions. Newer GLP-1 agonists may offer improved efficacy and user experience compared to this treatment.
  • Was this summary helpful?
Based on insights from Sermo’s triple verified physicians

Description

Bydureon BCise contains exenatide as its active ingredient, formulated as an extended-release injectable suspension. It is a GLP-1 receptor agonist, delivered subcutaneously via a sterile autoinjector. Each dose provides 2 mg of exenatide in a volume of 0.85 mL, using medium chain triglycerides as a key inactive ingredient.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected under the skin. You will be taught how to prepare and give it. Take it as directed on the prescription label at the same time every 7 days. Keep taking it unless your care team tells you to stop.

It is important that you put your used autoinjectors in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 10 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can, provided your next usual scheduled dose is due at least 3 days later. If you miss a dose and your next usual scheduled dose is due 1 or 2 days later, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store autoinjectors flat in a refrigerator. Do not freeze. This medication may be stored at room temperature between 15 and 30 degrees C (59 and 86 degrees F) for up to 4 weeks. Protect from light. Keep this medication in the original carton until you are ready to take it. Remove the autoinjector from the carton 15 minutes before it is time for you to take it. Use it immediately after you mix it. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Gallbladder problems—severe stomach pain, nausea, vomiting, fever
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
  • Thoughts of suicide or self-harm, worsening mood, feelings of depression
  • Thyroid cancer—new mass or lump in the neck, pain or trouble swallowing, trouble breathing, hoarseness
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Diarrhea
  • Loss of appetite
  • Nausea
  • Pain, redness, or irritation at injection site
  • Upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Gallbladder disease
  • Have had low platelet levels caused by medication
  • Have or have had pancreatitis
  • Having surgery
  • Kidney disease
  • Personal or family history of MEN 2, a condition that causes endocrine gland tumors
  • Personal or family history of thyroid cancer
  • Stomach or intestine problems, such as problems digesting food
  • An unusual or allergic reaction to exenatide, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

  • Acetaminophen
  • Digoxin
  • Estrogen and progestin hormones
  • Insulin and other medications for diabetes
  • Lisinopril
  • Lovastatin
  • Warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

You may need blood work done while you are taking this medication. Your care team will monitor your HbA1C (A1C). This test shows what your average blood sugar (glucose) level was over the past 2 to 3 months.

Know the symptoms of low blood sugar and know how to treat it. Always carry a source of quick sugar with you. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink if your blood sugar is too low and you are unable to care for yourself. Get medical help at once.

Tell your care team if you have high blood sugar. Your medication dose may change if your body is under stress. Some types of stress that may affect your blood sugar include fever, infection, and surgery.

Do not share pens or cartridges with anyone, even if the needle is changed. Each pen should only be used by one person. Sharing could cause an infection.

Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.

Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancer if you take this medication. Talk to your care team right away if you have a lump or swelling in your neck, hoarseness that does not go away, trouble swallowing, shortness of breath, or trouble breathing.

Make sure you stay hydrated while taking this medication. Drink water often. Eat fruits and veggies that have a high water content. Drink more water when it is hot or you are active. Talk to your care team right away if you have fever, infection, vomiting, diarrhea, or if you sweat a lot while taking this medication. The loss of too much body fluid may make it dangerous for you to take this medication.

If you are going to need surgery or a procedure, tell your care team that you are taking this medication.

Estrogen and progestin hormones that you take by mouth may not work as well while you are taking this medication. Talk to your care team about contraceptive options. They can help you find the option that works for you.

Do not take this medication without first talking to your care team if you may be or could become pregnant. Your care team can help you find the option that works for you. Weight loss is not recommended during pregnancy. Maintaining healthy blood sugar levels can help reduce the risk of pregnancy complications.

Talk to your care team if you are breastfeeding. When recommended, this medication may be taken. Its use during breastfeeding has not been well studied. Lactation may help lower your blood sugar levels. Your care team may recommend changes to your treatment plan.

What are the most serious risks of this medication?

This medication may increase the risk of thyroid tumors or cancer. Do not take this medication if you or a family member has or have had multiple endocrine neoplasia (MEN) 2 or a type of thyroid cancer called medullary thyroid carcinoma (MTC). Talk to your care team right away if you have a lump or swelling in the neck, pain or trouble swallowing, trouble breathing, or hoarseness.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

Terms of use

  1. Sermo Drug Ratings, and all information provided on this website, may not be used in combination with any artificial intelligence tool (including to train an algorithm, test, process, analyze, generate output and/or develop any form of artificial intelligence tool). 

  2. Visitors to the online patient-facing website at Sermo.com (“Sermo Drug Ratings”) are Authorized Users of the website, which contains data owned by a third-party provider, Elsevier, Inc.  Accordingly, by visiting Sermo Drug Ratings, Authorized User acknowledges that the website includes Elsevier owned data that Sermo licenses pursuant to a separate usage and Data agreement (the “Agreements”).  Authorized User further acknowledges that Sermo is a third-party beneficiary of the Agreements and Authorized User’s use of the website hereby binds them to the terms of the Agreements; provided, however, that Elsevier shall have no obligations or liability to an Authorized User whatsoever pursuant to the terms of the Agreements.

  3. Authorized User acknowledges and agrees that the Elsevier Products are designed for and are intended to be used by those residing in the United States, and that the information contained in the Elsevier Products does not comply with any laws or practices outside of the United States. You assume all responsibilities, duties, and obligations for any treatment, decision, or advice made or given to third parties as a result of the use or application of the Elsevier Products outside of the United States, and Sermo, Elsevier and its affiliates, subsidiaries, agents and suppliers will incur no liability for any use or application of the Products by Authorized Users outside of the United States.

Welcome to Sermo's Drug Ratings

Previously only for members, Sermo Drug Ratings are now openly available to all healthcare providers, patients, and industry professionals to support better healthcare decisions.

Clinical expertise
Insights based on real prescribing experience from triple-verified practicing physicians only
Detailed insights
Ratings on key attributes including efficacy, safety, tolerability, accessibility, and adherence
Unbiased reviews
Independent, physician-only reviews, free from pharmaceutical industry influence