JYNNEOS is a vaccine that contains the active ingredient Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN), a live, non-replicating orthopoxvirus. It is formulated as a suspension for subcutaneous injection and is available as a 0.5 mL dose. The vaccine is intended to provide immunity against smallpox and monkeypox. Key inactive ingredients include Tris (tromethamine) and sodium chloride, while it may also contain trace amounts of benzonase, gentamicin, and ciprofloxacin.
How should I use this medication?
This vaccine is injected under the skin. It is given by your care team.
This vaccine requires 2 doses to get the full benefit. Set a reminder for when your next dose is due.
A copy of Vaccine Information Statements will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This vaccine is only given by your care team. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Do not take this medication with any of the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular health checks.
Before you receive this vaccine, talk to your care team if you have an acute illness. Vaccines can be given to people with mild acute illness, such as the common cold or diarrhea. Discuss with your care team the risks and benefits of receiving this vaccine during a moderate to severe illness. Your care team may choose to wait to give you the vaccine when you feel better.
Cases of inflammation of the heart have been reported after receiving the smallpox vaccine. It is not known whether the smallpox and monkeypox vaccine causes heart inflammation. Talk to your care team right away if you are unusually weak or tired, have trouble breathing, chest pain, dizziness, fast or irregular heartbeat, fever, joint pain, swelling of the ankles, feet, hands or other unusual swelling. Adolescents or young adult males at an increased risk of inflammation of the heart may consider waiting 4 weeks after smallpox and monkeypox vaccination before getting an mRNA COVID-19 vaccine.
Report any side effects to your care team or to the Vaccine Adverse Events Reporting System (VAERS) website at https://vaers.hhs.gov. This is only for reporting side effects; VAERS staff do not give medical advice.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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