Letairis is the brand name for ambrisentan, an endothelin receptor antagonist selective for the endothelin type-A receptor. It is available in 5 mg and 10 mg film-coated tablets for once daily oral administration. The key inactive ingredients include croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose. The tablets are designed for oral administration, but the specific therapeutic use is not provided in the description section.
How should I use this medication?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. You can take this medication with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).
Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 1 month after the last dose. You will need a negative pregnancy test before, during, and after taking this medication. Contraception is recommended before starting this medication, during treatment, and for 1 month after the last dose. Progestin hormones may not work as well while you are taking this medication. Your care team can help you find the contraception option that works for you.
Because of the risks of birth defects, this medication is available only through a special program. Care teams, pharmacies, and patients must meet all the conditions of the program. Your care team will help you get signed up with the program if you need this medication.
Do not breastfeed while taking this medication and for 1 month after the last dose.
This medication may cause infertility. Talk to your care team if you are concerned about your fertility.
What are the most serious risks of this medication?
Do not take this medication if you may be pregnant. Serious fetal side effects may occur.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.
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