Lumizyme contains the active ingredient alglucosidase alfa, an enzyme that degrades glycogen. It is supplied as a sterile, white to off-white lyophilized powder for intravenous infusion. Each vial contains 50 mg of alglucosidase alfa along with inactive ingredients such as mannitol, polysorbate 80, and sodium phosphate. Alglucosidase alfa is intended to be used intravenously.
How should I use this medication?
This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. While this drug may be prescribed for children as young as newborns for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored carefully while you are receiving this medication.
The amount of fluid from this infusion may worsen existing lung or heart conditions. Your care team will watch you closely during and after your infusion if you are at risk.
This medication can cause serious allergic reactions. To reduce the risk, your care team may give you other medications to take before receiving this one. Follow the directions from your care team.
You may need blood work done while you are taking this medication.
You can be a part of a registry for patients with Pompe disease. This registry may ask for information over a long time. Ask your care team for more information.
What are the most serious risks of this medication?
Serious side effects may occur during the infusion of this medication. Your care team will watch you closely. Tell your care team right away if you have a skin rash, itching, hives, swelling of the face, tongue, arms, or legs, trouble breathing, fast or irregular heartbeat, or feel faint or lightheaded.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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