Mustargen ratings & reviews

Mechlorethamine Hydrochloride
Company: Merck S&D
Brand: Mustargen
Drug class: Antineoplastic and Immunomodulating Agents
+3 more
Antineoplastic and Immunomodulating Agents, Antineoplastics, Alkylating Agents, Nitrogen Mustard Analogs
Overall rating
3.4
full star full star full star empty star empty star
Ranked #1
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.7/5
Safety
3.3/5
Tolerability
3.2/5
Accessibility
3.1/5
Adherence
3.1/5

Sermo AI Overview

  • Mustargen is recognized for its historical significance in treating certain malignancies like Hodgkin's lymphoma, but its overall effectiveness, particularly for pleural and peritoneal effusions, is viewed negatively by specialists due to availability of more effective alternatives.
  • While some physicians report high safety and tolerability scores for Mustargen, concerns persist regarding its potential side effects and a variable efficacy profile, indicating mixed experiences among specialists.
  • Adherence to Mustargen varies significantly among patients, emphasizing the necessity for ongoing support to ensure consistent use, which is crucial for its effectiveness.
  • Concerns regarding the safety profile of Mustargen have been raised, particularly in regards to its side effects, necessitating careful monitoring during its use.
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Based on insights from Sermo’s triple verified physicians

Description

Mustargen is a medication containing mechlorethamine.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This drug is usually given as an injection into a vein or infused into a body cavity. It is administered in a hospital or clinic by a specially trained health care professional.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Where should I keep my medication?

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.

•signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine

•signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine

•signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness

•breathing problems

•changes in hearing

•feeling faint or lightheaded, falls

•pain, swelling, redness at site where injected

•unusual bleeding or bruising

•unusually weak or tired

•vomiting

•yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•diarrhea

•hair loss

•loss of appetite

•metallic taste or changes in taste

•missed menstrual periods

•nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

•blood disorders

•gout

•infection (especially a virus infection such as chickenpox, cold sores, or herpes)

•recent or ongoing radiation therapy

•an unusual or allergic reaction to mechlorethamine, other chemotherapy, other medicines, foods, dyes, or preservatives

•pregnant or trying to get pregnant

•breast-feeding

What may interact with this medication?

Do not take this medicine with any of the following medications:

•nalidixic acid

This medicine may also interact with the following medications:

•medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim

•vaccines

Talk to your doctor or health care professional before taking any of these medicines:

•acetaminophen

•aspirin

•ibuprofen

•ketoprofen

•naproxen

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor for checks on your progress. This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.

Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

Men should inform their doctor if they wish to father a child. This medicine may lower sperm counts.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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