Nitrostat ratings & reviews

Nitroglycerin
Company: Viatris
Brand: Nitrostat
+1 more
Nitrostat, RECTIV
Drug class: Cardiovascular System
+4 more
Cardiovascular System, Cardiac Therapy, Anti-anginal Agents, Nitrites and Nitrates, Nitrites and Nitrates, Plain
Overall rating
4.0
full star full star full star full star empty star
Ranked #2
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
4.3/5
Safety
3.9/5
Tolerability
3.8/5
Accessibility
4.1/5
Adherence
4.0/5

Sermo AI Overview

  • Nitrostat is noted for its favorable efficacy in treating angina, with healthcare professionals scoring its effectiveness highly, generally between 4.0 to 5.0. Patients typically experience good tolerability and adherence, suggesting it's well-managed and effective for relief.
  • While Nitrostat is generally well-tolerated, some variation in patient experiences could impact overall adherence, highlighting the importance of personalized treatment approaches.
  • Was this summary helpful?
Based on insights from Sermo’s triple verified physicians

Description

Nitrostat contains the active ingredient nitroglycerin in a 0.4 mg sublingual tablet form. Nitroglycerin is an organic nitrate and acts as a vasodilating agent. It is intended for sublingual administration and includes key inactive ingredients such as calcium stearate, colloidal silicon dioxide, and lactose monohydrate.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth as needed. Use at the first sign of an angina attack (chest pain or tightness). You can also take this medication 5 to 10 minutes before an event likely to produce chest pain. Follow the directions exactly as written on the prescription label. Place one tablet under your tongue and let it dissolve. Do not swallow whole. Replace the dose if you accidentally swallow it. It will help if your mouth is not dry. Saliva around the tablet will help it to dissolve more quickly. Do not eat or drink, smoke or chew tobacco while a tablet is dissolving. Sit down when taking this medication.

In an angina attack, you should feel better within 5 minutes after your first dose. You can take a dose every 5 minutes up to a total of 3 doses. If you do not feel better or feel worse after 1 dose, call 9-1-1 at once. Do not take more than 3 doses in 15 minutes. Your care team might give you other directions. Follow those directions if they do. Do not take your medication more often than directed.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is only used as needed.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Store in original container. Protect from light and moisture. Keep tightly closed. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Headache, unusual weakness or fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, blue skin or lips, which may be signs of methemoglobinemia
  • Increased pressure around the brain—severe headache, blurry vision, change in vision, nausea, vomiting
  • Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
  • Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
  • Worsening chest pain (angina)—pain, pressure, or tightness in the chest, neck, back, or arms

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Dizziness
  • Flushing
  • Headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Anemia
  • Head injury, recent stroke, or bleeding in the brain
  • Liver disease
  • Previous heart attack
  • An unusual or allergic reaction to nitroglycerin, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

Do not take this medication with any of the following:

  • Certain migraine medications, such as ergotamine and dihydroergotamine (DHE)
  • Medications used to treat erectile dysfunction, such as sildenafil, tadalafil, and vardenafil
  • Riociguat

This medication may also interact with the following:

  • Alteplase
  • Aspirin
  • Heparin
  • Medications for blood pressure
  • Medications for depression
  • Other medications used to treat angina
  • Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if you feel your medication is no longer working.

Keep this medication with you at all times. Sit or lie down when you take your medication to prevent falling if you feel dizzy or faint after using it. Try to remain calm. This will help you to feel better faster. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Do not treat yourself for coughs, colds, or pain while you are taking this medication without asking your care team for advice. Some ingredients may increase your blood pressure.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

Terms of use

  1. Sermo Drug Ratings, and all information provided on this website, may not be used in combination with any artificial intelligence tool (including to train an algorithm, test, process, analyze, generate output and/or develop any form of artificial intelligence tool). 

  2. Visitors to the online patient-facing website at Sermo.com (“Sermo Drug Ratings”) are Authorized Users of the website, which contains data owned by a third-party provider, Elsevier, Inc.  Accordingly, by visiting Sermo Drug Ratings, Authorized User acknowledges that the website includes Elsevier owned data that Sermo licenses pursuant to a separate usage and Data agreement (the “Agreements”).  Authorized User further acknowledges that Sermo is a third-party beneficiary of the Agreements and Authorized User’s use of the website hereby binds them to the terms of the Agreements; provided, however, that Elsevier shall have no obligations or liability to an Authorized User whatsoever pursuant to the terms of the Agreements.

  3. Authorized User acknowledges and agrees that the Elsevier Products are designed for and are intended to be used by those residing in the United States, and that the information contained in the Elsevier Products does not comply with any laws or practices outside of the United States. You assume all responsibilities, duties, and obligations for any treatment, decision, or advice made or given to third parties as a result of the use or application of the Elsevier Products outside of the United States, and Sermo, Elsevier and its affiliates, subsidiaries, agents and suppliers will incur no liability for any use or application of the Products by Authorized Users outside of the United States.

Welcome to Sermo's Drug Ratings

Previously only for members, Sermo Drug Ratings are now openly available to all healthcare providers, patients, and industry professionals to support better healthcare decisions.

Clinical expertise
Insights based on real prescribing experience from triple-verified practicing physicians only
Detailed insights
Ratings on key attributes including efficacy, safety, tolerability, accessibility, and adherence
Unbiased reviews
Independent, physician-only reviews, free from pharmaceutical industry influence