Nitrolingual ratings & reviews

Nitrolingual is a brand of nitroglycerin, an organic nitrate and vasodilator. It is available as a lingual spray that delivers 400 mcg of nitroglycerin per spray, with options of 60 or 200 metered sprays on or under the tongue. Key inactive ingredients include medium-chain triglycerides, dehydrated alcohol, medium-chain partial glycerides, and peppermint oil. It is intended to relax blood vessels to reduce the workload on the heart.

How should I use this medication?

This medication is only for use in the mouth. Use at the first sign of an attack. You can also use this medication 5 to 10 minutes before an event likely to produce chest pain. Follow the directions exactly as written on the prescription label. Do not shake the container. Remove the plastic cover. Before using this medication for the first time, you must prime the bottle by spraying the pump 5 times into the air away from yourself. If this medication has not been used for 6 weeks, you must re-prime the bottle by spraying once into the air away from yourself. Hold the container upright and spray either onto or underneath the tongue. Do not breathe in the spray. After each spray, close your mouth but do not swallow or rinse. Sit down to take this medication.

In an angina attack, you should feel better within 5 minutes after your first dose. You can take a dose every 5 minutes up to a total of 3 doses. If you do not feel better or feel worse after 1 dose, call 9-1-1 at once. Do not take more than 3 doses in 15 minutes. Your care team might give you other directions. Follow those directions if they do. Do not take your medication more often than directed.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. This medication is only used as needed.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Do not spray near flames. Do not forcefully open or burn the container. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Headache, unusual weakness or fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, blue skin or lips, which may be signs of methemoglobinemia
• Increased pressure around the brain—severe headache, blurry vision, change in vision, nausea, vomiting
• Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
• Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
• Worsening chest pain (angina)—pain, pressure, or tightness in the chest, neck, back, or arms

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Dizziness
• Flushing
• Headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Liver disease
• Recent heart attack
• An unusual or allergic reaction to nitroglycerin, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

What may interact with this medication?

Do not take this medication with any of the following:

• Certain migraine medications, such as ergotamine and dihydroergotamine (DHE)
• Medications used to treat erectile dysfunction, such as sildenafil, tadalafil, and vardenafil
• Riociguat

This medication may also interact with the following:

• Medications for blood pressure

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your care team if you feel your medication is no longer working.

Keep this medication with you at all times. Sit or lie down when you take your medication to prevent falling if you feel dizzy or faint after using it. Try to remain calm. This will help you to feel better faster. If you feel dizzy, take several deep breaths and lie down with your feet propped up, or bend forward with your head resting between your knees.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Do not treat yourself for coughs, colds, or pain while you are taking this medication without asking your care team for advice. Some ingredients may increase your blood pressure.