SymlinPen is an anti-diabetic medication containing the active ingredient pramlintide acetate, a synthetic analog of the hormone amylin. It is available as a clear, isotonic, sterile solution for subcutaneous injection. The formulation includes pramlintide at a concentration of 1000 mcg/mL and key inactive ingredients like metacresol, D-mannitol, and acetic acid. SymlinPen is intended to help manage blood sugar levels in patients with diabetes who are also treated with insulin.
How should I use this medication?
This medication is for injection under the skin. You will be taught how to prepare and give this medication. Use exactly as directed. Do not mix this medication with insulin in the same syringe. Take this medication immediately before meals. Take your medication at regular intervals. Do not take your medication more often than directed.
Always check the appearance of this medication before using it. Do not use it if it is cloudy or has solid particles in it.
It is important that you put your used needles and injector-pens in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
It is important not to miss a dose. Your care team should discuss a plan for missed doses with you. If you do miss a dose, follow their plan. Do not take double doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store unopened injector-pens in the refrigerator between 2 to 8 degrees C (36 to 46 degrees F). Do not freeze. Throw away any unused medication after the expiration date.
Store opened injector-pens (pens currently in use) in the refrigerator or at room temperature of not greater than 30 degrees C (86 degrees F) for up to 30 days. Do not freeze. Keeping this medication at room temperature decreases the amount of pain during injection. Throw away any opened pens of this medication 30 days after opening.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Many medications may cause changes in blood sugar, these include:
Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress.
A test called the HbA1C (A1C) will be monitored. This is a simple blood test. It measures your blood sugar control over the last 2 to 3 months. You will receive this test every 3 to 6 months.
Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.
Always carry a quick-source of sugar with you in case you have symptoms of low blood sugar. Examples include hard sugar candy or glucose tablets. Make sure others know that you can choke if you eat or drink when you develop serious symptoms of low blood sugar, such as seizures or unconsciousness. They must get medical help at once.
Tell your care team if you have high blood sugar. You might need to change the dose of your medication. If you are sick or exercising more than usual, you might need to change the dose of your medication.
Do not skip meals. Ask your care team if you should avoid alcohol. Many nonprescription cough and cold products contain sugar or alcohol. These can affect blood sugar.
Pens should never be shared. Even if the needle is changed, sharing may result in passing of viruses like hepatitis or HIV.
Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medication and dosage times.
What are the most serious risks of this medication?
This medicine can cause severe low blood sugar, usually within 3 hours after an injection. Have a plan to treat low blood sugar. You should have fast-acting sugar (such as hard candy, glucose tablets, juice) or a glucagon injection with you at all times. Monitor your blood sugar regularly. If you have severe low blood sugar or if you have low blood sugar more often than normal, call your healthcare provider.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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