Zilbrysq contains the active ingredient zilucoplan, a complement inhibitor, presented in the form of a synthetic macrocyclic peptide. It is available as a sterile, preservative-free solution for subcutaneous injection in single-dose prefilled syringes, with strengths of 16.6 mg /0.416 mL, 23 mg /0.574 mL, and 32.4 mg/0.81 mL. Key inactive ingredients include dibasic sodium phosphate, monobasic sodium phosphate, sodium chloride, and water for injection.
How should I use this medication?
This medication is injected under the skin. You will be taught how to prepare and give it. Take it as directed on the prescription label at the same time every day. Keep taking it unless your care team tells you to stop.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store in a refrigerator or at room temperature up to 30 degrees C (86 degrees F). Keep prefilled syringes in the original carton. Protect from light. Once opened, prefilled syringes must be used right away.
Refrigeration (preferred): Store in the refrigerator. Do not freeze. Get rid of any unused medication after the expiration date.
Room temperature: This medication may be stored at room temperature for up to 3 months. If it is stored at room temperature, get rid of any unused medication after 3 months or after it expires, whichever is first. Do not return this medication to the refrigerator after it has been stored at room temperature.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions have not been studied.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Talk to your care team about your vaccination history. To lower your risk of infection, you may need certain vaccines before you start this medication.
What are the most serious risks of this medication?
This medication lowers your body’s ability to fight off infection. This may increase the risk of serious infections, such as meningitis. Talk to your care team about what vaccines you have received. You may need certain vaccines before you start this medication. This will help lower your risk of infection. Seek medical help right away if you have fever, neck pain or stiffness, sensitivity to light, headache, nausea, vomiting, or confusion.
Source: This information is sourced from Elsevier Inc.
The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.
Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.
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