Adcirca ratings & reviews

Tadalafil
Company: United Therapeutics
Brand: Adcirca
+2 more
Adcirca, ALYQ, Cialis
Drug class: Genito-urinary System and Sex Hormones
+8 more
Genito-urinary System and Sex Hormones, Cardiovascular System, Urologicals, Cardiac Therapy, Pulmonary Hypertension (PAH) Agents, Sexual Dysfunction Agents, Erectile Dysfunction (ED) Agents, Phosphodiesterase Inhibitors for PAH, Phosphodiesterase Inhibitors for ED
Overall rating
3.5
full star full star full star half star empty star
Ranked #3
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.8/5
Safety
3.4/5
Tolerability
3.6/5
Accessibility
3.2/5
Adherence
3.6/5

Sermo AI Overview

  • Adcirca is generally regarded as an effective treatment for pulmonary hypertension and erectile dysfunction, with its efficacy rated positively by healthcare professionals. However, accessibility and insurance coverage issues may limit its use.
  • While Adcirca is well-tolerated and preferred for its longer half-life in erectile dysfunction, some patients find financial barriers that restrict its availability. Additionally, its efficacy is noted to be less favorable in benign prostatic hyperplasia (BPH).
  • There are ongoing concerns about Adcirca's differentiation from other treatments for pulmonary hypertension and the limitations in its effectiveness and accessibility for certain conditions, urging patients to discuss alternatives with their healthcare providers.
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Based on insights from Sermo’s triple verified physicians

Description

Adcirca contains the active ingredient tadalafil in its USP form, a selective inhibitor of the PDE5 enzyme. It comes as almond-shaped tablets with dosages of 2.5 mg, 5 mg, 10 mg, and 20 mg, taken orally. Key inactive ingredients include croscarmellose sodium, povidone, and lactose monohydrate.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the prescription label. You can take this medication with or without food. Take your medication at regular intervals. Take both tablets at the same time, one after the other. Do not split your dose throughout the day. Do not take it more often than directed. Do not stop taking except on your care team's advice.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Hearing loss or ringing in ears
  • Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
  • Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
  • Prolonged or painful erection
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
  • Sudden vision loss in one or both eyes

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Back pain
  • Facial flushing or redness
  • Headache
  • Muscle pain
  • Runny or stuffy nose
  • Upset stomach

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Abnormal penis shape or Peyronie disease
  • Bleeding disorder
  • Blood diseases, such as sickle cell anemia or leukemia
  • Eye disease, such as retinitis pigmentosa
  • Have had a heart attack
  • Have had a painful and prolonged erection
  • Have had a stroke
  • Heart disease, such as angina, heart failure, irregular heartbeat or rhythm
  • High or low blood pressure
  • Kidney disease
  • Liver disease
  • Pulmonary vascular occlusive disease (PVOD)
  • Stomach ulcers, other stomach or intestine problems
  • An unusual or allergic reaction to tadalafil, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

Do not take this medication with any of the following:

  • Medications for erectile dysfunction, such as avanafil, sildenafil, vardenafil
  • Nitrates, such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin
  • Other tadalafil products (Cialis)
  • Riociguat

This medication may also interact with the following:

  • Certain medications for high blood pressure
  • Certain medications for HIV or AIDS
  • Certain medications used for fungal infections, such as fluconazole, itraconazole, ketoconazole, voriconazole
  • Certain medications used for seizures, such as carbamazepine, phenytoin, phenobarbital
  • Grapefruit juice
  • Macrolide antibiotics, such as clarithromycin or erythromycin
  • Medications for prostate conditions
  • Rifabutin, rifampin, or rifapentine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

Stop and call your care team right away if you have symptoms such as nausea, dizziness, or chest pain during sex.

Contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects. Do not have more than 4 alcohol-containing drinks in a short period of time while taking this medication.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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