Depo-Testosterone ratings & reviews

Testosterone Cypionate
Company: Pfizer
Brand: Depo-Testosterone
Drug class: Genito-urinary System and Sex Hormones
+2 more
Genito-urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System, Androgens
Overall rating
3.5
full star full star full star half star empty star
Ranked #13
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.9/5
Safety
3.4/5
Tolerability
3.5/5
Accessibility
3.4/5
Adherence
3.4/5

Sermo AI Overview

  • Depo-Testosterone is often effective for treating hypogonadism, particularly in women with low libido, though overall patient satisfaction can vary. However, there are significant barriers to access and coverage that frustrate patients and physicians.
  • While generally safe, concerns exist over the liver risks associated with Depo-Testosterone, leading to mixed reviews on its safety despite some positive feedback regarding accessibility and effectiveness in hypogonadism.
  • Depo-Testosterone is viewed as having weak efficacy for palliative breast cancer treatment based on low ratings from hematologists and gynecologists, suggesting limitations in its applications beyond hypogonadism.
  • Many patients report pain from injections, which can discourage self-administration of Depo-Testosterone, although many still find it effective for their conditions despite the discomfort.
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Based on insights from Sermo’s triple verified physicians

Description

Depo-testosterone contains the active ingredient testosterone cypionate, which is an oil-soluble ester of testosterone. It belongs to a class of drugs known as androgen hormones. The drug is formulated as an injectable solution, available in 100 mg/mL and 200 mg/mL strengths, intended for intramuscular administration. Key inactive ingredients include benzyl benzoate, cottonseed oil, and benzyl alcohol.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected into a muscle. It is given by your care team in a hospital or clinic setting.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Contact your care team about the use of this medication in children. While it be prescribed for children as young as 12 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Try not to miss a dose. Your care team will tell you when your next injection is due. Notify the office if you are unable to keep an appointment.

Where should I keep my medication?

Keep out of the reach of children. This medication can be abused. Keep your medication in a safe place to protect it from theft. Do not share this medication with anyone. Selling or giving away this medication is dangerous and against the law.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze. Protect from light. Follow the directions for the product you are prescribed. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
  • Heart attack—pain or tightness in the chest, shoulders, arms or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
  • Increase in blood pressure
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing of the skin or eyes, unusual weakness or fatigue
  • Mood swings, irritability, or hostility
  • Prolonged or painful erection
  • Sleep apnea—loud snoring, gasping during sleep, daytime sleepiness
  • Stroke—sudden numbness or weakness of the face, arm or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
  • Swelling of the ankles, hands, or feet
  • Thoughts of suicide or self-harm, worsening mood, feelings of depression

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Acne
  • Change in sex drive or performance
  • Pain, redness, or irritation at the application site
  • Unexpected breast tissue growth

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Cancer
  • Diabetes
  • Heart disease
  • Kidney disease
  • Liver disease
  • Lung disease
  • Prostate disease
  • An unusual or allergic reaction to testosterone, other medications, foods, dyes, or preservatives
  • If you or your partner are pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

  • Medications for diabetes
  • Medications that treat or prevent blood clots like warfarin
  • Oxyphenbutazone
  • Propranolol
  • Steroid medications like prednisone or cortisone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. They will need to check the level of testosterone in your blood.

Heart attacks and strokes have been reported with the use of this medication. Get emergency help if you develop signs or symptoms of a heart attack or stroke. Talk to your care team about the risks and benefits of this medication.

This medication may affect blood sugar levels. If you have diabetes, check with your care team before you change your diet or the dose of your diabetic medication.

Talk to your care team if you wish to become pregnant or think you might be pregnant. This medication can cause serious birth defects if taken during pregnancy.

This medication is banned from use in athletes by most athletic organizations.

What are the most serious risks of this medication?

This medication can cause serious and life-threatening allergic reactions. These reactions may occur with your first dose or at any time during treatment. Your care team will watch you closely. Tell your care team right away if you have a skin rash, itching, hives, swelling of the face, tongue, arms, or legs, trouble breathing, fast or irregular heartbeat, or feel faint or lightheaded.

This medicine is for injection into a muscle only. Rarely, serious reactions can occur after an injection. You will be monitored for 30 minutes after receiving each injection. Tell your health care provider right away and seek emergency medical help if you have coughing, shortness of breath, difficulty breathing, sweating, throat tightening, chest pain, dizziness or fainting after receiving an injection.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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