The brand name of the vaccine is Gardasil 9. Its active ingredients are virus-like particles from the L1 protein of various HPV types, specifically as a non-infectious recombinant 9-valent vaccine. Gardasil 9 is a sterile liquid suspension intended for intramuscular administration, with each 0.5-mL dose containing HPV L1 proteins and approximately 500 mcg of aluminum as an adjuvant. Key inactive ingredients include sodium chloride, L-histidine, polysorbate 80, sodium borate, a small amount of yeast protein, and water for injection.

How should I use this medication?

This vaccine is injected into a muscle. It is given by your care team.

This vaccine requires 2 or 3 doses to get the full benefit. Set a reminder for when your next dose is due.

A copy of the Vaccine Information Statement will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 9 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

Keep appointments for follow-up doses as directed. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

Where should I keep my medication?

This vaccine is only given by your care team. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Feeling faint or lightheaded

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Diarrhea
• Dizziness
• Fatigue
• Fever
• Headache
• Nausea
• Pain, redness, irritation, or bruising at the injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Fever
• Hemophilia
• HIV or AIDS
• Immune system problems
• Infection
• Low platelets
• An unusual reaction to human papillomavirus vaccine, yeast, other vaccines, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

What may interact with this medication?

• Certain medications for arthritis
• Medications for organ transplant
• Medications to treat cancer
• Steroid medications, such as prednisone or cortisone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team regularly.

Report any side effects to your care team right away.

This vaccine, like all vaccines, may not fully protect everyone.