Linzess ratings & reviews

Linaclotide
Company: Allergan
Brand: Linzess
Drug class: Alimentary Tract and Metabolism
+7 more
Alimentary Tract and Metabolism, Agents for Functional Gastrointestinal Disorder, Agents for Functional Bowel Disorder, Agents for Irritable Bowel Syndrome (IBS), Agents for Functional Gastrointestinal Constipation Disorders, Agents for Constipation-Predominant IBS (IBS-C), Guanylate Cyclase-C Agonists for Constipation, Guanylate Cyclase-C Agonists for IBS-C
Overall rating
3.6
full star full star full star half star empty star
Ranked #1
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.8/5
Safety
3.7/5
Tolerability
3.6/5
Accessibility
3.1/5
Adherence
3.5/5

Sermo AI Overview

  • Linzess is often considered a treatment option when other therapies for constipation or IBS have not been successful, highlighting its role as a secondary choice in patient care and varying acceptance among healthcare providers.
  • Linzess is generally effective for treating constipation and irritable bowel syndrome (IBS), especially in cases like opioid-induced constipation, with many patients and physicians noting positive outcomes and its utility as a treatment option.
  • While most patients tolerate Linzess well, there are reports of side effects like diarrhea affecting a notable portion of users, indicating the need for careful management and patient education before starting treatment.
  • Despite its benefits, Linzess is perceived as expensive and can be challenging for patients to access, which limits its wider use and leads some to see it as a less favorable option compared to other treatments.
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Based on insights from Sermo’s triple verified physicians

Description

LINACLOTIDE (lin a KLOE tide) treats irritable bowel syndrome (IBS) with constipation. It may also treat chronic constipation. It works by softening the stool, making it easier to have a bowel movement.

Dosage & Administration

How should I use this medication?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medication. Swallow the capsules whole. Take it on an empty stomach, at least 30 minutes before a meal. If you have trouble swallowing, you may open the capsule and mix with applesauce or water. Keep taking it unless your care team tells you to stop. How to take with applesauce: Open the capsule and put the contents in 1 teaspoon of applesauce. Swallow the medication and applesauce right away. Do not chew the medication or applesauce. Do not store for later use. How to take with water: Pour 30 mL (1 ounce) of room temperature bottled water into a clean cup. Open the capsule and sprinkle all the beads into the cup of water. Swirl the mixture for at least 20 seconds. Drink the mixture right away. If beads remain in the cup, add 30 mL more of water and swirl. Drink the mixture right away. Do not store for later use. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team about the use of this medication in children. While it may be given to children as young as 6 years for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.

Where should I keep my medication?

Keep out of the reach of children and pets. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medication in the original container. Protect from moisture. Keep the container tightly closed. Do not throw out the packet in the container. It keeps the medication dry. Get rid of any unused medication after the expiration date. To get rid of medications that are no longer needed or have expired: -Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location. -If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible: -Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): -Bloating -Diarrhea -Gas -Stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions: -Diarrhea -History of blockage in your bowels -History of stool (fecal) impaction -An unusual or allergic reaction to linaclotide, other medications, foods, dyes, or preservatives -Pregnant or trying to get pregnant -Breast-feeding

What may interact with this medication?

-Interactions have not been studied.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. Diarrhea is a common side effect of this medication. It often begins within 2 weeks of starting this medication. Stop taking this medication and call your care team if you get severe diarrhea. Stop taking this medication and call your care team or go to the nearest hospital emergency room right away if you develop unusual or severe stomach pain, especially if you also have bright red, bloody stools or black stools that look like tar.

What are the most serious risks of this medication?

NEVER give this medication to children younger than 2 years of age. It may cause serious dehydration and harm.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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