Mysoline ratings & reviews

Primidone
Company: Bausch
Brand: Mysoline
Drug class: Central and Peripheral Nervous System
+2 more
Central and Peripheral Nervous System, Anticonvulsants, Anticonvulsants, Barbiturates
Overall rating
3.3
full star full star full star empty star empty star
Ranked #12
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.3/5
Safety
3.3/5
Tolerability
3.2/5
Accessibility
3.6/5
Adherence
3.3/5

Sermo AI Overview

  • Mysoline is generally tolerated well by some users, showing effectiveness in treating tonic-clonic seizures. However, there are concerns from neurologists regarding its tolerability and the availability of newer, better alternative medications.
  • While some physicians recognize Mysoline as a reliable option for partial seizures, feedback on its tolerability varies. Many suggest considering other medications due to Mysoline's significant side effects that may limit its use.
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Based on insights from Sermo’s triple verified physicians

Description

Mysoline's active ingredient is primidone, which is not formulated as a base or salt. The drug is presented in tablet form, available in 50 mg and 250 mg dosages for oral use. Key inactive ingredients include lactose monohydrate, methylcellulose, and sodium starch glycolate.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medication more often than directed. Do not stop taking except on the advice of your care team.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Contact your care team about the use of this medication in children. Special care may be needed. While this medication may be prescribed for children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

This medication may cause accidental overdose and death if it is taken by other adults, children, or pets. Mix any unused medication with a substance like cat litter or coffee grounds. Then throw the medication away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medication after the expiration date.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F).

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • CNS depression—slow or shallow breathing, shortness of breath, feeling faint, dizziness, confusion, trouble staying awake
  • Thoughts of suicide or self-harm, worsening mood, or feelings of depression

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Dizziness
  • Drowsiness
  • Loss of balance or coordination
  • Nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Kidney disease
  • Liver disease
  • Porphyria
  • Suicidal thoughts, plans, or attempt by you or a family member
  • An unusual or allergic reaction to primidone, phenobarbital, other barbiturates or seizure medications, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

Do not take this medication with any of the following:

  • Voriconazole

This medication may also interact with the following:

  • Antivirals for HIV or AIDS
  • Cyclosporine
  • Disopyramide
  • Doxycycline
  • Estrogen and progestin hormones
  • Medications for cancer
  • Medications for depression, anxiety, or other mental health conditions
  • Modafinil
  • Prescription pain medications
  • Quinidine
  • Warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. It may be 2 to 3 weeks before you see the full effects of this medication.

Do not suddenly stop taking this medication. You may increase the risk of seizures. Your care team will tell you how much medication to take. If your care team wants you to stop the medication, the dose may be slowly lowered over time.

Wear a medical ID bracelet or chain to say you have epilepsy. Carry a card that describes your condition. List the medications and doses you take on the card.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Estrogen and progestin hormones may not work as well while you are taking this medication. Your care team can help you find the contraceptive option that works for you.

This medication may cause thoughts of suicide or depression. This includes sudden changes in mood, behaviors, or thoughts. These changes can happen at any time but are more common in the beginning of treatment or after a change in dose. Call your care team right away if you experience these thoughts or worsening depression.

People who become pregnant while using this medication may enroll in the North American Antiepileptic Drug Pregnancy Registry by calling 1-888-233-2334. This registry collects information about the safety of antiepileptic medication use during pregnancy.

This medication may cause a decrease in vitamin D and folic acid. You should make sure that you get enough vitamins while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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