What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Asian ancestry
- Bone marrow disease
- Glaucoma
- Heart disease
- Irregular heartbeat or rhythm
- Kidney disease
- Liver disease
- Low blood cell levels (white cells, red cells, or platelets)
- Mental health conditions
- Porphyria
- Suicidal thoughts, plans, or attempt by you or a family member
- An unusual or allergic reaction to carbamazepine, other medications, foods, dyes, or preservatives
- Pregnant or trying to get pregnant
- Breastfeeding
What may interact with this medication?
Do not take this medication with any of the following:
- Certain medications for HIV or AIDS that are given in combination with cobicistat
- Delavirdine
- MAOIs, such as Carbex, Eldepryl, Marplan, Nardil, and Parnate
- Nefazodone
- Oxcarbazepine
This medication may also interact with the following:
- Acetaminophen
- Acetazolamide
- Barbiturate medications for inducing sleep or treating seizures, such as phenobarbital
- Certain antibiotics, such as clarithromycin, erythromycin, or troleandomycin
- Cimetidine
- Cyclosporine
- Danazol
- Dicumarol
- Doxycycline
- Estrogen or progestin hormones
- Grapefruit juice
- Isoniazid, INH
- Levothyroxine and other thyroid hormones
- Lithium
- Loratadine
- Medications for angina or blood pressure
- Medications for cancer
- Medications for depression, anxiety, or other mental health conditions
- Medications for fungal infections, such as fluconazole, itraconazole, or ketoconazole
- Medications for HIV or AIDS
- Medications for seizures
- Medications that help you fall asleep
- Methadone
- Niacinamide
- Praziquantel
- Propoxyphene
- Rifampin or rifabutin
- Steroid medications, such as prednisone or cortisone
- Theophylline
- Tramadol
- Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Do not suddenly stop taking this medication. You may develop a severe reaction. Your care team will tell you how much medication to take. If your care team wants you to stop the medication, the dose may be slowly lowered over time to avoid any side effects.
You may need blood work done while you are taking this medication.
This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.
This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Talk to your care team right away if you have fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or you might notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.
This medication can cause new or worsening depression and increase the risk of suicidal thoughts and actions in a small number of people. This can happen while you are taking this medication or after stopping it. Talk to your care team right away if you have changes in mood or behavior or thoughts of self-harm or suicide. They can help you.
This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and sunscreen. Do not use sun lamps, tanning beds, or tanning booths.
This medication contains an inactive ingredient that is safe in small amounts. It can cause serious side effects in large amounts. The risk for side effects is increased in young children and in people with kidney or liver problems. Tell your care team about all the medications you take. Talk to your care team right away if you have trouble breathing, weakness or fatigue, confusion, or a loss of balance or coordination.
Wear a medical ID bracelet or chain. Carry a card that describes your condition. List the medications and doses you take on the card.
Estrogen and progestin hormones may not work as well while you are taking this medication. Your care team can help you find the contraceptive option that works for you.
Talk to your care team if you may be pregnant. People who become pregnant while taking this medication can enroll in the North American Antiepileptic Drug Pregnancy Registry by calling 1-888-233-2334. This registry collects information about the safety of this medication during pregnancy.
What are the most serious risks of this medication?
This medicine can lower blood counts, like red blood cells and platelets. This is rare, but is very serious when it happens. Your health care provider will check you blood counts while you take this medicine.
This medicine can stop healthy white blood cells from being made. This is rare but is very serious when it happens. Your health care provider will check your blood counts while you take this medicine.
People of Asian descent may need a genetic blood test before taking this medicine. Asian patients are more likely to have a genetic variation called HLA-B*1502. This may increase the risk of serious rash with this medicine.
This medication may cause rare but serious skin rashes.