What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Diabetes
- Hemophilia
- High cholesterol or triglycerides
- Liver disease
- An unusual or allergic reaction to ritonavir, other medications, foods, dyes, or preservatives
- Pregnant or trying to get pregnant
- Breast-feeding
What may interact with this medication?
Do not take this medication with any of the following:
- Alfuzosin
- Apalutamide
- Certain medications for irregular heartbeat, such as amiodarone, bepridil, dofetilide, dronedarone, flecainide, propafenone, quinidine
- Cobicistat
- Conivaptan
- Elagolix
- Eletriptan
- Eliglustat
- Enzalutamide
- Eplerenone
- Ergot alkaloids, such as dihydroergotamine, ergonovine, ergotamine, methylergonovine
- Flibanserin
- Idelalisib
- Isavuconazonium
- Ivabradine
- Lomitapide
- Lovastatin
- Lurasidone
- Meperidine
- Naloxegol
- Pergolide
- Pimozide
- Ranolazine
- Red yeast rice
- Rifampin
- Silodosin
- Simvastatin
- St. John's wort
- Terfenadine
- Tinidazole
- Tolvaptan
- Triazolam
- Voriconazole
This medication may also interact with the following:
- Atovaquone
- Bedaquiline
- Bosentan
- Certain medications for blood pressure, heart disease, irregular heartbeat, such as digoxin, disopyramide, lidocaine, mexiletine, metoprolol, timolol
- Certain medications for cancer, such as dasatinib, ibrutinib, nilotinib, venetoclax, vinblastine, vincristine
- Certain medications for cholesterol, such as atorvastatin, rosuvastatin
- Certain medications for depression, anxiety, or mental health conditions, such as amitriptyline, bupropion, desipramine, fluoxetine, nefazodone, nortriptyline, paroxetine, perphenazine, quetiapine, risperidone, thioridazine, trazodone
- Certain medications for erectile dysfunction, such as avanafil, sildenafil, tadalafil, vardenafil
- Certain medications for fungal infections, such as fluconazole, itraconazole, posaconazole
- Certain medications for seizures, such as carbamazepine, clonazepam, ethosuximide, divalproex, lamotrigine, phenytoin
- Certain medications for sleep, such as buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem
- Certain medications that treat or prevent blood clots, such as warfarin, rivaroxaban
- Clarithromycin
- Colchicine
- Cyclosporine
- Dronabinol
- Estrogen and progestin hormones
- Methamphetamine
- Metronidazole
- Opioid medications for pain
- Other antivirals for HIV
- Quinine
- Rifabutin
- Salmeterol
- Simeprevir
- Sirolimus
- Steroid medications, such as betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, prednisolone, triamcinolone
- Tacrolimus
- Theophylline
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Discuss any new symptoms with your care team. You will need to have important blood work done while taking this medication.
HIV is spread to others through sexual or blood contact. Talk to your care team about how to stop the spread of HIV.
Estrogen and progestin hormones may not work as well while you are taking this medication. If you are using these hormones for contraception, talk to your care team about using a second type of contraception. A barrier contraceptive, such as a condom or diaphragm, is recommended.
This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.
What are the most serious risks of this medication?
Tell your healthcare provider all the prescriptions, over-the-counter medicines, vitamins, and supplements you take. This medicine has interactions with many other medicines. It can stop some medicines from working how they are supposed to. It can make the side effects of other medicines worse. If you are given a new medicine, make sure your healthcare provider knows you are taking this one.