Reyataz ratings & reviews

Atazanavir
Company: BMS
Brand: Reyataz
Drug class: General Anti-infectives Systemic
+3 more
General Anti-infectives Systemic, Antivirals For Systemic Use, HIV Antivirals, Protease Inhibitors
Overall rating
3.5
full star full star full star half star empty star
Ranked #24
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.6/5
Safety
3.5/5
Tolerability
3.4/5
Accessibility
3.6/5
Adherence
3.5/5

Sermo AI Overview

  • Reyataz is generally effective in managing HIV infection, especially when used in combination therapies. Its once-daily dosing is appreciated by physicians, potentially improving patient adherence to the treatment.
  • Despite its efficacy, there are concerns related to potential side effects, particularly the risk of jaundice, and a perception that Reyataz has a less favorable profile compared to newer HIV medications.
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Based on insights from Sermo’s triple verified physicians

Description

Reyataz capsules contain the active ingredient atazanavir sulfate, which is an HIV-1 protease inhibitor. The capsules are available in dosage strengths of 150 mg, 200 mg, and 300 mg of atazanavir and are designed for oral administration. Key inactive ingredients include crospovidone, lactose monohydrate, and magnesium stearate. The medication is intended to manage the symptoms of HIV by limiting the spread of the virus in the body.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth with water. Take it with food.

For your therapy to work as well as possible, take each dose exactly as prescribed on the prescription label. Do not skip doses. Skipping doses may make the HIV virus resistant to this medication and other medications. Keep taking this therapy unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer wanted or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Gallbladder problems—severe stomach pain, nausea, vomiting, fever
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Infection—fever, chills, cough, or sore throat
  • Kidney stones—blood in the urine, pain or trouble passing urine, pain in the lower back or sides
  • Lipodystrophy—increased fat in the upper back or midsection, decreased fat in the face, arms, or legs
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Rash, fever, and swollen lymph nodes
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea
  • Dizziness
  • Headache
  • Muscle pain
  • Nausea
  • Stomach pain
  • Trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Diabetes
  • Hemophilia
  • Irregular heartbeat
  • Kidney disease
  • Liver disease
  • An unusual or allergic reaction to atazanavir, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

Do not take this medication with any of the following:

  • Alfuzosin
  • Belinostat
  • Certain antivirals for HIV or hepatitis, such as darunavir, indinavir, saquinavir, nevirapine, tipranavir, elbasvir; grazoprevir; glecaprevir; pibrentasvir
  • Certain benzodiazepines, such as alprazolam, oral midazolam, triazolam
  • Certain medications for cancer, such as apalutamide, encorafenib, enzalutamide, irinotecan, ivosidenib, mitotane, pacritinib, ribociclib
  • Certain medication for heart conditions, such as eplerenone, ivabradine, mavacamten, sildenafil (for pulmonary hypertension)
  • Certain medications for cholesterol, such as lomitapide, lovastatin, simvastatin
  • Certain medications for migraines, such as eletriptan, ubrogepant
  • Certain medications for seizures, such as carbamazepine, phenytoin, phenobarbital
  • Cisapride
  • Conivaptan
  • Elagolix
  • Ergot alkaloids, such as dihydroergotamine, ergotamine, methylergonovine
  • Finerenone
  • Flibanserin
  • Isovuconazonium
  • Lonafarnib
  • Naloxegol
  • Pimozide
  • PPIs, such as lansoprazole, omeprazole, pantoprazole, rabeprazole
  • Red yeast rice
  • Rifampin
  • St. John's wort
  • Tolvaptan
  • Voclosporin

This medication may also interact with the following:

  • Lurasidone
  • Certain medications for stomach problems, such as antacids, cimetidine, famotidine
  • Estrogen and progestin hormones
  • Other medication that cause heart rhythm changes, such as amiodarone or quinidine

This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Discuss any new symptoms with your care team. You will need to have important blood work done while on this medication.

HIV is spread to others through sexual or blood contact. Talk to your care team about how to stop the spread of HIV.

This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.

Estrogen or progestin hormones may not work as well while you are taking this medication. If you are using these hormones for contraception, talk to your care team about using a second type of contraception. A barrier contraceptive, such as a condom or diaphragm, is recommended.

This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

This medication may affect how well your kidneys work. Drink plenty of fluids while taking this medication to stay hydrated.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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