PERJETA contains the active ingredient pertuzumab, a recombinant humanized monoclonal antibody targeting HER2. It is intended for intravenous infusion as a sterile, clear to slightly opalescent liquid in single-dose vials containing 420 mg of pertuzumab. Key inactive ingredients include L-histidine acetate, sucrose, and polysorbate 20.
How should I use this medication?
This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
This medication is not approved for use in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored carefully while you are receiving this medication. This medication may make you feel generally unwell. This is not uncommon in medications used to treat cancer. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.
You may need a test to check your heart before and during treatment. Talk to your care team right away if you have coughing, shortness of breath, swelling of the ankles, feet, or hands, fatigue, or an increased heart rate.
Talk to your care team if you may be pregnant. Serious fetal side effects can occur if you take this medication during pregnancy and for 7 months after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 7 months after the last dose. Your care team can help you find the option that works for you.
Do not breastfeed while taking this medication and for 7 months after the last dose.
What are the most serious risks of this medication?
This medication may cause serious birth defects if taken during pregnancy. Do not take this medication if you are pregnant.
This medication may cause new or worsening heart failure. Talk to your care team right away if you have shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, weakness, or fatigue.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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