VALCHLOR ratings & reviews

Valchlor contains the active ingredient mechlorethamine HCl, an alkylating drug. It is formulated as a gel for topical use, with each tube containing 0.016% w/w mechlorethamine in a base of various inactive ingredients, including diethylene glycol monoethyl ether and propylene glycol. Valchlor is designed to be applied on the skin.

How should I use this medication?

This medication is for external use only. Do not take by mouth. Use it as directed on the prescription label. Apply to completely dry skin at least 4 hours before or 30 minutes after showering or washing. Wash hands before and after use. Caregivers should wear disposable gloves to apply medication. Avoid applying this medication inside your eyes, nose, and mouth. Allow skin to dry for 5 to 10 minutes before covering with clothing. You may apply moisturizers to treated areas 2 hours before or 2 hours after applying this medication. Do not wear air or water tight coverings over affected skin area. Keep using it unless your care team tells you to stop.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store in the refrigerator. Keep this medication in the original box. Use within 30 minutes of taking out of the refrigerator. Return the tube to the refrigerator after each use. Talk with your pharmacist if the tube has been out of the refrigerator for more than 1 hour a day. Get rid of any unused medication after 90 days.

This medication is flammable. Avoid exposure to heat, fire, flame, and smoking.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to empty in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• Burning, itching, crusting, or peeling of treated skin

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Change in skin color
• Mild skin irritation, redness, or dryness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• An unusual or allergic reaction to mechlorethamine, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

What may interact with this medication?

Interactions are not expected with this medication.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.

This medication can transfer from your body to others. If a person or pet comes in contact with the medication, they may have serious side effects. If you cannot avoid skin-to-skin contact, cover the application site with clothing. If accidental contact happens, wash the skin of the person or pet right away with soap and water.

Do not get this medication in your eyes. If you do, rinse out with plenty of cool tap water.

Talk to your care team about your risk of cancer. You may be more at risk for certain types of cancers if you take this medication.

Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy. Contraception is recommended while taking this medication. Your care team can help you find the option that works for you.

If your partner can get pregnant, use a condom during sex while taking this medication.

Do not breastfeed while taking this medication.

This medication may cause infertility. Talk to your care team if you are concerned about your fertility.