Afinitor DISPERZ ratings & reviews

Afinitor Disperz is a medication containing the active ingredient everolimus in the form of tablets for oral suspension. Everolimus is a kinase inhibitor. The medication is available in dosage strengths of 2 mg, 3 mg, or 5 mg for oral administration. Key inactive ingredients include butylated hydroxytoluene, colloidal silicon dioxide, and microcrystalline cellulose.

How should I use this medication?

Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Leave the tablets in the sealed pack until you are ready to take your dose. Prepare a suspension for each dose. You can take it with or without food. You should always take it the same way. Your care team may change your dose or tell you stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.

When using a syringe to make the suspension: Place the tablet(s) into a 10-mL syringe. Add 5 mL of water and 4 mL of air to the syringe. Hold the syringe with the tip up for 3 minutes, until the tablets are dissolved. Turn the syringe over 5 times before taking the medication. Then, add another 5 mL of water and 4 mL of air to the syringe, swirl the contents, and take right away. This ensures you received your entire dose. Take the dose within 60 minutes of mixing.

When using a drinking glass to make the suspension: Place the tablet(s) in 25 mL of water. Let the tablets dissolve for 3 minutes, then gently swirl just before drinking. Then, add another 25 mL of water to the glass, swirl the contents, and take right away. This ensures you received your entire dose. Take the dose within 60 minutes of mixing.

Do not take this medication with grapefruit juice.

Handling this medication may be harmful. Wear gloves while touching the medication. Talk to your care team about how to handle this medication. Special instructions may apply.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can unless it is more than 6 hours late. If it is more than 6 hours late, skip the missed dose. Take the next dose at the normal time.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Keep this medication in the original packaging until you are ready to take it. Get rid of any prepared suspension that is not used within 60 minutes of mixing.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions or angioedema—skin rash, itching or hives, swelling of the face, eyes, lips, tongue, arms, or legs, trouble swallowing or breathing
• Dry cough, shortness of breath or trouble breathing
• High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
• Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
• Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
• Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
• Unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

• Diarrhea
• Headache
• Pain, redness, or swelling with sores inside the mouth or throat
• Stomach pain
• Swelling of the ankles, hands, or feet

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Diabetes
• Having or recent surgery
• High cholesterol
• History of hepatitis B
• Infection
• Kidney disease
• Liver disease
• Low blood cell levels (white cells, red cells, and platelets)
• Lung disease
• Recent or ongoing radiation
• Recent or upcoming vaccine
• An unusual or allergic reaction to everolimus, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

What may interact with this medication?

Do not take this medication with any of the following:

• Live virus vaccines
• Thioridazine

This medication may also interact with the following:

• Certain antibiotics, such as clarithromycin, erythromycin, rifampin
• Certain antivirals for HIV or hepatitis
• Certain medications for blood pressure, heart disease, or irregular heartbeat
• Certain medications for fungal infections
• Certain medications for seizures
• Grapefruit juice
• Medications that lower your chance of fighting an infection
• St. John's wort

Other medications may affect the way this medication works. Talk with your care team about all of the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. You may need blood work while you are taking this medication.

This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.

This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

Before having surgery, talk to your care team to make sure it is ok. This medication can increase the risk of poor healing of your surgical site or wound. You will need to stop this medication for 7 days before surgery. After surgery, wait at least 2 weeks before restarting this medication. Make sure the surgical site or wound is healed enough before restarting this medication. Talk to your care team if you have questions.

This medication may increase your risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

Avoid taking medications that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your care team. These medications may hide a fever.

Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medication.

This medication can increase bad cholesterol and fats (such as LDL, triglycerides) and decrease good cholesterol (HDL) in your blood. You may need blood tests to check your cholesterol. Ask your care team what you can do to lower your risk of high cholesterol while taking this medication.

Tell your care team if you develop a rash or redness that in an area of the body that has previously had radiation therapy.

Some products come in blister cards. Some of the blisters may have desiccants in them. A desiccant helps protect your medication from moisture. Do not eat the desiccant. Talk to your pharmacist if you have questions.

Talk to your care team if you or your partner may be pregnant. This medication can cause serious birth defects if taken during pregnancy and for 8 weeks after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 8 weeks after the last dose. Your care team can help you find the option that works for you.

If your partner can get pregnant, use a condom during sex while taking this medication and for 4 weeks after the last dose.

Do not breastfeed while taking this medication and for 2 weeks after the last dose.

This medication may cause infertility. Talk to your care team if you are concerned about your fertility.