Intron A ratings & reviews

Interferon Alfa-2b
Company: Merck S&D
Brand: Intron A
Drug class: General Anti-infectives Systemic
+7 more
General Anti-infectives Systemic, Antineoplastic and Immunomodulating Agents, Immunostimulating Agents, Antivirals For Systemic Use, Interferons, Hepatitis Antivirals, Interferons, Alpha, Interferons for Hepatitis B and C
Overall rating
3.3
full star full star full star empty star empty star
Ranked #4
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.0/5
Safety
3.7/5
Tolerability
3.1/5
Accessibility
3.3/5
Adherence
3.2/5

Sermo AI Overview

  • Overall, Intron A is perceived as having weak efficacy across multiple indications, particularly in treating malignant melanoma, non-Hodgkin's lymphoma, and hepatitis C, with average ratings often around 2.0 out of 5 from various specialties.
  • Concerns regarding safety and tolerability of Intron A persist, with high discontinuation rates noted due to side effects, leading many physicians to caution against its use as a first-line treatment option in several cases.
  • Despite its limitations, some specialists still acknowledge Intron A as a viable option for specific conditions like West Nile virus and hairy-cell leukemia, indicating it may provide symptom improvement if well tolerated.
  • Physician feedback reflects mixed opinions about Intron A's effectiveness for newer viral infections like hepatitis B and treatment for condylomata acuminata, with ratings suggesting it may not be the best available therapy.
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Based on insights from Sermo’s triple verified physicians

Description

The brand name is Intron A.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected into a muscle or under the skin or infused into a vein. It is usually given by your care team in a hospital or clinic setting. It may also be given at home.

If you get this medication at home, you will be taught how to prepare and give it. Use exactly as directed. Take it as directed on the prescription label at the same time every day. Take all of this medication unless your care team tells you to stop it early. Keep taking it even if you think you are better.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store in the refrigerator. Do not freeze. If you are using the powder, it should be used immediately after mixing or may be stored in the refrigerator for up to 24 hours. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Aplastic anemia—unusual weakness or fatigue, dizziness, headache, trouble breathing, increased bleeding or bruising
  • Dizziness, loss of balance or coordination, confusion or trouble speaking
  • Dry cough, shortness of breath or trouble breathing
  • Eye pain, change in vision, vision loss
  • Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • High thyroid levels (hyperthyroidism)—fast or irregular heartbeat, weight loss, excessive sweating or sensitivity to heat, tremors or shaking, anxiety, nervousness, irregular menstrual cycle or spotting
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
  • Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression
  • Lupus-like syndrome—joint pain, swelling, or stiffness, butterfly-shaped rash on the face, rashes that get worse in the sun, fever, unusual weakness or fatigue
  • Mood and behavior changes—anxiety, nervousness, confusion, hallucinations, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
  • Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
  • Pulmonary hypertension—shortness of breath, chest pain, fast or irregular heartbeat, feeling faint or lightheaded, fatigue, swelling of the ankles or feet
  • Raynaud syndrome—cool, numb, or painful fingers or toes that may change color from pale, to blue, to red
  • Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
  • Unusual bruising or bleeding
  • Unusual weakness or fatigue, fever, headache, skin rash, muscle or joint pain, loss of appetite, pain, tingling, or numbness in the hands or feet

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Diarrhea
  • Flu-like symptoms—fever, chills, muscle pain, cough, headache, fatigue
  • Nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Autoimmune disease
  • Blood or bleeding disorders
  • Bone marrow disease
  • Depression or other mental health condition
  • Diabetes
  • Heart or lung disease
  • Kidney or liver disease
  • Thyroid disease
  • An unusual or allergic reaction to interferons, E. coli protein, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breast-feeding

What may interact with this medication?

  • Theophylline
  • Zidovudine, AZT

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. You may need blood work while taking this medication.

Do not change brands of this medication without consulting your care team. Different brands of this medication can act differently in your body. Check with your pharmacist if your refills do not look like your original product.

This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

This medication may make you feel generally unwell. This is not uncommon as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your care team tells you to stop.

This medication may increase the risk of getting an infection. Call your care team for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

This medication may increase your risk to bruise or bleed. Call your care team if you notice any unusual bleeding.

What are the most serious risks of this medication?

This medicine can lower your body’s ability to fight infections. You may get more infections while taking this medicine. Any infection you get could become serious and even deadly.

This medicine can increase the risk of having a stroke.

This medicine can cause serious mental health problems. Patients of all ages and their families should watch for changes, especially sudden changes in mood, behaviors, thoughts, or feelings. Some symptoms to watch for are depression, thoughts of suicide, aggressive behavior, wanting to hurt others, hostility, anger, anxiety, irritability, being suspicious or distrustful, or any unusual or extreme changes in behavior or mood. Call your healthcare provider right away for new or worsening mental problems. Call your healthcare provider as needed, especially if you are worried about symptoms.

This medicine can cause heart problems or make heart problems worse.

This medicine can cause immune system disorders or make them worse. Examples are rheumatoid arthritis, lupus, sarcoidosis, thyroid disease, and psoriasis. Tell your healthcare provider if you have any kind of immune disease.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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