The brand name of the drug is Pulmozyme. The active ingredient is dornase alfa, a recombinant form of human deoxyribonuclease I (rhDNase). Pulmozyme is designed as an inhalation solution for administration via a nebulizer system. Each dose contains 2.5 mL of a sterile, clear, colorless solution with dornase alfa, calcium chloride dihydrate, and sodium chloride as key inactive ingredients.
How should I use this medication?
This medication is for inhalation using a nebulizer. Nebulizers make a liquid into an aerosol that you breathe in through your mouth or your mouth and nose and into your lungs. Do not mix this medication with other medications in the nebulizer. Take it as directed on the prescription label. Do not use it more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed. While this medication may be prescribed for children as young as 5 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store in a refrigerator or at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Avoid exposure to extreme heat.
Refrigeration (preferred): Store in the refrigerator. Keep unopened vials in the foil pouch. Do not open a vial until you are ready to use it. An opened vial must be used right away. Throw away any unused medication after the expiration date.
Room Temperature: This medication may be stored at room temperature for up to 24 hours. Keep unopened vials in the foil pouch. Do not open a vial until you are ready to use it. An opened vial must be used right away. If it is stored at room temperature, throw away any unused medication after 24 hours.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions are not expected. Do not mix with any other medications in the nebulizer.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.
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