Margenza contains the active ingredient margetuximab-cmkb, a HER2/neu receptor antagonist and monoclonal antibody. This drug is available as an injectable solution for intravenous use, with each single-dose vial containing 250 mg of the active ingredient. Key inactive ingredients include L-arginine hydrochloride, polysorbate 80, and sucrose. It is a clear to slightly opalescent solution that requires dilution before use.
How should I use this medication?
This medication is infused into a vein. It is given by your care team in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored carefully while you are receiving this medication.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 4 months after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 4 months after the last dose. Your care team can help you find the option that works for you.
Do not breastfeed while taking this medication and for 4 months after the last dose.
What are the most serious risks of this medication?
If you can become pregnant, you will need a test to make sure you are not pregnant before starting this medication. You must use contraception while taking this medication. You may need to keep using contraception even after you stop taking the medication. This depends on the medication. It is important to talk to your care team about how long to use contraception. Call your care team right away if you think you may be pregnant, have unprotected sex, or if you think your contraception did not work.
This medicine may cause heart problems, including decreased heart function or heart failure.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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