Phenytek ratings & reviews

Phenytoin
Company: Viatris
Brand: Phenytek
+1 more
Phenytek, Dilantin
Drug class: Central and Peripheral Nervous System
+2 more
Central and Peripheral Nervous System, Anticonvulsants, Anticonvulsants, Hydantoins
Overall rating
3.5
full star full star full star half star empty star
Ranked #21
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.7/5
Safety
3.4/5
Tolerability
3.3/5
Accessibility
3.9/5
Adherence
3.4/5

Sermo AI Overview

  • Phenytek is generally considered effective for managing seizures, particularly tonic-clonic and partial seizures, with many physicians noting its suitability as a second-line option. However, careful patient selection and close monitoring are essential due to safety concerns and potential toxicity.
  • While Phenytek is recognized for its accessibility and tolerability, health professionals also express concerns about its safety profile, particularly for specific populations like women of childbearing age. This suggests a need for ongoing evaluation against newer alternatives.
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Based on insights from Sermo’s triple verified physicians

Description

Phenytek contains phenytoin sodium in an extended capsule form, available in 200 mg and 300 mg doses for oral administration. It is related to barbiturates and includes inactive ingredients such as colloidal silicon dioxide and gelatin. Phenytek is designed for slow and extended absorption, differing from immediate-release versions of phenytoin sodium.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. You can take it with or without food. You should always take it the same way. Keep taking it unless your care team tells you to stop.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your care team about the use of this medication in children. While it may be prescribed for to children for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medication after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
  • Infection—fever, chills, cough, or sore throat
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Phenytoin toxicity—uncontrollable eye movements, loss of balance or coordination, trouble speaking, unusual weakness or fatigue, nausea, vomiting
  • Rash, fever, and swollen lymph nodes
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
  • Swollen lymph nodes in the neck, groin, chest, or underarm area
  • Thoughts of suicide or self-harm, worsening mood, or feelings of depression
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

  • Difficulty with paying attention, memory, or speech
  • Dizziness
  • Drowsiness
  • Headache

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Alcohol use disorder
  • Asian ancestry
  • Blood disorders or disease
  • Diabetes
  • Heart problems
  • Kidney disease
  • Liver disease
  • Porphyria
  • Recent or ongoing radiation
  • Suicidal thoughts, plans, or attempt by you or a family member
  • Thyroid disease
  • An unusual or allergic reaction to phenytoin, other medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

Do not take this medication with any of the following:

  • Artemether
  • Certain antivirals for HIV or hepatitis
  • Idelalisib
  • Isavuconazonium
  • Lonafarnib
  • Lorlatinib
  • Lumefantrine
  • Lurasidone
  • Pacritinib
  • Praziquantel
  • Ranolazine

This medication may also interact with the following:

  • Albendazole
  • Alcohol
  • Aspirin and aspirin-like medications
  • Bleomycin
  • Capecitabine
  • Carboplatin
  • Certain medications for blood pressure, heart disease, irregular heartbeat
  • Certain medications for depression, anxiety, or other mental health conditions
  • Certain medications for cholesterol, such as atorvastatin, fluvastatin, simvastatin
  • Certain medications for fungal infections, such as fluconazole, itraconazole, ketoconazole, miconazole, posaconazole, voriconazole
  • Certain medications for seizures, such as carbamazepine, ethosuximide, felbamate, lacosamide, lamotrigine, methsuximide, oxcarbazepine, phenobarbital, topiramate, valproic acid, vigabatrin
  • Certain medications for stomach problems, such as antacids, cimetidine, omeprazole, sucralfate
  • Certain medications that prevent or treat blood clots, such as warfarin, apixaban, dabigatran, edoxaban, and rivaroxaban
  • Chloramphenicol
  • Chlorpropamide
  • Cisplatin
  • Cyclosporine
  • Disulfiram
  • Doxorubicin
  • Doxycycline
  • Estrogen or progestin hormones
  • Fluorouracil
  • Folic acid
  • Irinotecan
  • Isoniazid
  • Medications that relax muscles for surgery
  • Methadone
  • Methotrexate
  • Methylphenidate
  • Paclitaxel
  • Phenothiazines, such as chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • Rifampin
  • St. John's wort
  • Steroid medications, such as prednisone or cortisone
  • Sulfadiazine
  • Sulfamethoxazole
  • Teniposide
  • Theophylline
  • Ticagrelor
  • Ticlopidine
  • Tolbutamide
  • Vitamin D

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. This medication needs careful monitoring. Your care team may schedule regular blood tests.

This medication may cause serious skin reactions. They can happen weeks to months after starting the medication. Contact your care team right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. You may also notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medication and dosage times.

Do not change brands or dosage forms of this medication without discussing the change with your care team.

This medication may affect your coordination, reaction time, or judgment. Do not drive or operate machinery until you know how this medication affects you. Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects.

Estrogen and progestin hormones may not work as well while you are taking this medication. A barrier contraceptive, such as a condom or diaphragm, is recommended if you are using these hormones for contraception. Talk to your care team about effective forms of contraception.

This medication can cause tooth and gum problems. Tenderness, swelling, or minor bleeding of the gums may occur. Brushing and flossing your teeth regularly may reduce the risk of side effects. Visit your dentist on a regular basis. Tell your dentist about any medications you are taking.

Do not take antacids at the same time as this medication. If you get an upset stomach and want to take an antacid or medication for diarrhea, make sure there is an interval of 2 to 3 hours before or after you took your phenytoin.

This medication may cause thoughts of suicide or depression. This includes sudden changes in mood, behaviors, or thoughts. These changes can happen at any time but are more common in the beginning of treatment or after a change in dose. Call your care team right away if you experience these thoughts or worsening depression.

Those who become pregnant while using this medication may enroll in the North American Antiepileptic Drug Pregnancy Registry by calling 1-888-233-2334. This registry collects information about the safety of antiepileptic medication use during pregnancy.

This medication may cause a decrease in vitamin D and folic acid. You should make sure that you get enough vitamins while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.

Source: This information is sourced from Elsevier Inc.

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The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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