SYFOVRE is a drug containing the active ingredient pegcetacoplan in the form of an injection. Pegcetacoplan is a complement inhibitor and is administered through an intravitreal injection as a clear, colorless to light yellow aqueous solution. Each vial allows for the delivery of 0.1 mL of solution containing 15 mg of pegcetacoplan. The formulation includes inactive ingredients like trehalose dihydrate, glacial acetic acid, sodium acetate trihydrate, and Water for Injection.
How should I use this medication?
This medication is injected into the eye. It is given by a care team that specializes in this treatment. It will be given in a hospital or clinic setting.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Keep appointments for follow-up doses. It is important not to miss your dose. Call your care team if you are unable to keep an appointment.
Where should I keep my medication?
This medication is given in a hospital or clinic. It will not be stored at home.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
What may interact with this medication?
Interactions are not expected. Do not use any other eye products without talking to your care team.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Tell your care team if your symptoms do not start to get better or if they get worse. Regular eye exams will be needed while you are being treated with this medication.
Talk to your care team if you wish to become pregnant or think you might be pregnant. A reliable form of contraception is recommended while taking this medication and for 40 days after stopping treatment. Talk to your care team about reliable forms of contraception.
Tell your care team right away if you have any change in your eyesight.
Source: This information is sourced from Elsevier Inc.
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Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.
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