Crixivan ratings & reviews

Indinavir
Company: Merck S&D
Brand: Crixivan
Drug class: General Anti-infectives Systemic
+3 more
General Anti-infectives Systemic, Antivirals For Systemic Use, HIV Antivirals, Protease Inhibitors
Overall rating
3.2
full star full star full star empty star empty star
Ranked #37
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
3.4/5
Safety
3.2/5
Tolerability
3.1/5
Accessibility
3.1/5
Adherence
3.0/5

Sermo AI Overview

  • Crixivan is generally perceived as having weak efficacy for treating HIV, with a low composite efficacy rating from infectious disease specialists, which may limit its current use in clinical practice.
  • Healthcare providers note that more cost-effective and equally effective alternatives to Crixivan are available for HIV treatment, reflecting a shift in preference toward modern therapies.
  • Although Crixivan is recognized for its accessibility and tolerability, there is a consensus among physicians to favor newer, more effective treatment options for HIV.
  • Was this summary helpful?
Based on insights from Sermo’s triple verified physicians

Description

The brand name is Crixivan. The active ingredient is not specified in the Description section. This drug is described as an antiretroviral medicine. The formulation, dosage strengths, and route of administration are not provided.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

Take this medication by mouth with a full glass of water. Take it on an empty stomach, at least 1 hour before or 2 hours after food. You may also take it with a light meal, like dry toast with jelly, juice, and coffee with skim milk and sugar; or corn flakes, skim milk, and sugar. For your therapy to work as well as possible, take each dose exactly as prescribed on the prescription label. Do not skip doses. Skipping doses can make the HIV virus resistant to this and other medications. Keep taking this therapy unless your care team tells you to stop.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose by more than 2 hours, wait and take the next dose at the regular time. But, if you miss a dose by less than 2 hours, take your missed dose right away. Then take your next dose at the regular time. Do not take double or extra doses.

Where should I keep my medication?

Keep out of the reach of children and pets.

Store between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer wanted or have expired:

  • Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
  • If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substances. Seal the mixture in a bag or container. Put it in the trash.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • blood in the urine
  • breathing problems
  • dark urine
  • dizziness
  • general ill feeling or flu-like symptoms
  • light-colored stools
  • loss of appetite, nausea
  • pain in the lower back or side
  • pain when urinating
  • signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • right upper belly pain
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • nausea, vomiting
  • stomach pain
  • weight gain around waist, back, or thinning of face, arms, legs

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Diabetes
  • Hemophilia
  • Kidney disease
  • Liver disease
  • An unusual or allergic reaction to indinavir, other medications, foods, dyes, or preservatives
  • Breast-feeding
  • Pregnancy or recent attempts to get pregnant

What may interact with this medication?

Do not take this medication with any of the following:

  • Alprazolam
  • Amiodarone
  • Astemizole
  • Atazanavir
  • Cisapride
  • Conivaptan
  • Lurasidone
  • Medications for headaches, such as dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • Medications for high cholesterol, such as cerivastatin, lovastatin, simvastatin
  • Midazolam
  • Naloxegol
  • Pimozide
  • Ranolazine
  • Rifampin
  • Rifapentine
  • Red yeast rice
  • St. John's wort
  • Triazolam

This medication may also interact with the following:

  • Atorvastatin
  • Carbamazepine
  • Clarithromycin
  • Cyclosporine
  • Dexamethasone
  • Fluticasone
  • Medications for blood pressure, such as amlodipine, felodipine, nifedipine
  • Medications for depression, anxiety, or mental health disorders
  • Medications for erectile dysfunction
  • Medications for fungal infections, such as ketoconazole and itraconazole
  • Medications for irregular heartbeat, such as dofetilide, lidocaine, quinidine
  • Other medications for HIV
  • Phenytoin
  • Phenobarbital
  • Rifabutin
  • Sirolimus
  • Tacrolimus

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular checks on your progress. Discuss any new symptoms with your care team. You will need to have important blood work done while taking this medication.

HIV is spread to others through sexual or blood contact. Talk to your care team about how to stop the spread of HIV.

Estrogen and/or progestin hormones may not work as well while you are taking this medication. If you are using these hormones for contraception, talk to your care team about using a second type of contraception. A barrier contraceptive, such as a condom or diaphragm, is recommended.

This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.

This medication may cause kidney stones. To help avoid kidney stones, drink plenty of fluids while taking this medication. Adults should drink at least six 8-ounce glasses of liquids (preferably water) throughout the day, every day. Call your care team if you notice pain or difficulty passing urine.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

Terms of use

  1. Sermo Drug Ratings, and all information provided on this website, may not be used in combination with any artificial intelligence tool (including to train an algorithm, test, process, analyze, generate output and/or develop any form of artificial intelligence tool). 

  2. Visitors to the online patient-facing website at Sermo.com (“Sermo Drug Ratings”) are Authorized Users of the website, which contains data owned by a third-party provider, Elsevier, Inc.  Accordingly, by visiting Sermo Drug Ratings, Authorized User acknowledges that the website includes Elsevier owned data that Sermo licenses pursuant to a separate usage and Data agreement (the “Agreements”).  Authorized User further acknowledges that Sermo is a third-party beneficiary of the Agreements and Authorized User’s use of the website hereby binds them to the terms of the Agreements; provided, however, that Elsevier shall have no obligations or liability to an Authorized User whatsoever pursuant to the terms of the Agreements.

  3. Authorized User acknowledges and agrees that the Elsevier Products are designed for and are intended to be used by those residing in the United States, and that the information contained in the Elsevier Products does not comply with any laws or practices outside of the United States. You assume all responsibilities, duties, and obligations for any treatment, decision, or advice made or given to third parties as a result of the use or application of the Elsevier Products outside of the United States, and Sermo, Elsevier and its affiliates, subsidiaries, agents and suppliers will incur no liability for any use or application of the Products by Authorized Users outside of the United States.

Welcome to Sermo's Drug Ratings

Previously only for members, Sermo Drug Ratings are now openly available to all healthcare providers, patients, and industry professionals to support better healthcare decisions.

Clinical expertise
Insights based on real prescribing experience from triple-verified practicing physicians only
Detailed insights
Ratings on key attributes including efficacy, safety, tolerability, accessibility, and adherence
Unbiased reviews
Independent, physician-only reviews, free from pharmaceutical industry influence