PENBRAYA ratings & reviews

Neisseria Meningitidis Group A Capsular Polysaccharide Tetanus Toxoid Conjugate antigen, Neisseria Meningitidis Group C Capsular Polysaccharide Tetanus Toxoid Conjugate antigen, Neisseria Meningitidis Group W-135 Capsular Polysaccharide Tetanus Toxoid Conjugate antigen, Neisseria Meningitidis Group Y Capsular Polysaccharide Tetanus Toxoid Conjugate antigen;Neisseria Meningitidis Serogroup B Recombinant LP2086 A05 Protein Variant antigen, Neisseria Meningitidis Serogroup B Recombinant LP2086 B01 Protein Variant antigen
Company: Pfizer
Brand: PENBRAYA
Drug class: General Anti-infectives Systemic
+3 more
General Anti-infectives Systemic, Vaccines, Pure Vaccines, Meningococcal Vaccines, All Types
Overall rating
4.0
full star full star full star full star empty star
Ranked #1
Physician ratings
  • Efficacy: effective for its intended use
  • Safety: safe to use in humans
  • Tolerability: low drug side effects
  • Accessibility: insurance/payer coverage, cost, affordability,formulary coverage, availability in your hospital or practice setting
  • Adherence: patient compliance with treatment
Efficacy
4.1/5
Safety
4.2/5
Tolerability
4.1/5
Accessibility
3.7/5
Adherence
3.8/5

Sermo AI Overview

  • PENBRAYA is generally viewed as a safe option for meningococcal infection prophylaxis, particularly for pediatric patients, as indicated by strong safety ratings from healthcare providers.
  • There are noted challenges with patient adherence to PENBRAYA, especially among pediatricians, suggesting that while effective, compliance could be improved for better outcomes.
  • Despite positive ratings on efficacy, some physicians expressed concerns about accessibility, specifically around cost and insurance reimbursement, which may hinder the use of PENBRAYA.
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Based on insights from Sermo’s triple verified physicians

Description

PENBRAYA is a vaccine containing active components for Meningococcal Groups A, B, C, W, and Y. It is a suspension intended for intramuscular injection, consisting of a Lyophilized MenACWY Component reconstituted with a MenB Component. Key inactive ingredients include L-histidine, trometamol, sucrose, aluminum phosphate, sodium chloride, and polysorbate 80. PENBRAYA is designed to protect against meningococcal infections caused by these serogroups.

Source: This information is sourced from FDA and powered by AI

Dosage & Administration

How should I use this medication?

This medication is injected into a muscle. It is given by your care team.

This vaccine requires 2 doses to get the full benefit. Set a reminder for when your next dose is due. It is important you get the same type or brand of vaccine for both doses. Keep a record of which vaccine you received.

A copy of Vaccine Information Statements will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often. A copy of Vaccine Information Statements will be given before each vaccination. Be sure to read this information carefully each time. This sheet may change often.

Talk to your care team to see which vaccines are right for you. Some vaccines should not be used in all age groups.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

Where should I keep my medication?

This vaccine is only given by your care team. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Side Effects

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Feeling faint or lightheaded

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Chills
  • General discomfort and fatigue
  • Headache
  • Joint pain
  • Muscle pain
  • Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings & Precautions

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • Bleeding disorder
  • Fever or infection
  • History of fainting
  • History of Guillain-Barre syndrome
  • Immune system problems
  • An unusual or allergic reaction to meningococcal vaccine, other vaccines, medications, foods, dyes, or preservatives
  • Pregnant or trying to get pregnant
  • Breastfeeding

What may interact with this medication?

  • Medications that lower your chance of fighting infection

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your care team for regular health checks.

Report any side effects to your care team or to the Vaccine Adverse Event Reporting System (VAERS) website at https://vaers.hhs.gov. This is only for reporting side effects; VAERs staff do not give medical advice.

Source: This information is sourced from Elsevier Inc.

Disclaimer

The reviews, ratings, comments, and opinions expressed on this platform are solely those of the individual medical professionals who posted them and do not reflect the views or positions of Sermo, Inc. Sermo does not endorse, verify, or validate the content of individual reviews. The information provided is user-generated and reflects personal clinical experiences, which may not be complete, accurate, or applicable to your specific health needs. It is not intended as medical advice.

Prescription medications affect individuals differently, and what works for one person may not work for another. Always consult your doctor, pharmacist, or other qualified healthcare provider to ensure the information displayed applies to your personal circumstances. Only a licensed healthcare provider can advise you on what is safe and effective for you.

Keep all medications out of the reach of children, never share your medicine with others, and use each medication only as prescribed. Your reliance on any information provided on this platform is at your own risk.

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